ArticleFrontiers in psychiatry2019
Treating Depression With Tai Chi: State of the Art and Future Perspectives.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 7 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Effects of different mind-body exercises on quality of life and cancer-related fatigue in breast cancer survivors: a systematic review and network meta-analysis.Journal of cancer survivorship : research and practice · 2026Pooled it
- The effects of traditional Chinese exercises on anxiety and depression in adults: a systematic review and network meta-analysis.Frontiers in public health · 2025Pooled it
- Effects of digitalized traditional Chinese exercises on the physical and mental health and quality of life of older adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2025Pooled it
- Tai Chi Exercise for Mental and Physical Well-Being in Patients with Depressive Symptoms: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Mindfulness-Based Movement Intervention to Improve Sleep Quality: A Meta-Analysis and Moderator Analysis of Randomized Clinical Trials.International journal of environmental research and public health · 2022Pooled it
- Stress management interventions for adults with heart failure: Systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Pooled it
- Mind-Body Physical Activity Interventions and Stress-Related Physiological Markers in Educational Settings: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Tai chi in mental health interventions: a narrative review comparing its role with pharmacotherapy and psychotherapy.Frontiers in psychology · 2026Review
- Mild Cognitive Impairment and Suicidal Ideation Among Adults Aged 65 Years or Older From Low- and Middle-Income Countries.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Global research trends in the effects of exercise on depression: A bibliometric study over the past two decades.Heliyon · 2024Review
- Department of Veterans Affairs Healthcare Provider Perceptions of Confidence Following a Wheelchair/Adaptive Tai Chi Chuan Training.American journal of lifestyle medicine · 2024Article
- Effects of Tai Chi in diabetes patients: Insights from recent research.World journal of diabetes · 2024Article
- Evaluating the impact of tai chi therapy on stress reduction among older adults.Bioinformation · 2024Article
- Differences in brain connectivity between older adults practicing Tai Chi and Water Aerobics: a case-control study.Frontiers in integrative neuroscience · 2024Article
- The effects of an acute Tai Chi on emotional memory and prefrontal cortex activation: a fNIRS study.Frontiers in behavioral neuroscience · 2024Article
- Effect of Tai Chi on Young Adults with Subthreshold Depression via a Stress-Reward Complex: A Randomized Controlled Trial.Sports medicine - open · 2023Article
- Tai Chi exercise improves working memory capacity and emotion regulation ability.Frontiers in psychology · 2023Article
- The Use of Kinesthetic Empathy with Adults Living with Treatment Resistant Depression: A Survey Study.American journal of dance therapy · 2022Article
- TraditionalFrontiers in cardiovascular medicine · 2022Article
- The Effect of Tai Chi Chuan on Emotional Health: Potential Mechanisms and Prefrontal Cortex Hypothesis.Evidence-based complementary and alternative medicine : eCAM · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Major depressive disorder (MDD) is one of the most prevalent mental illnesses in America. Current treatments for MDD are unsatisfactory given high non-response rates, high relapse rates, and undesirable side effects. Accumulating evidence suggests that Tai Chi, a popular mind-body intervention that originated as a martial art, can significantly regulate emotion and relieve the symptoms of mood disorders. In addition, the availability of instructional videos and the development of more simplified and less structured Tai Chi has made it a promising low-intensity mind-body exercise. In this article, we first examine a number of clinical trials that implemented Tai Chi as a treatment for depression. Then, we explore several mechanisms by which Tai Chi may alleviate depressive symptoms, hypothesizing that the intervention may modulate the activity and connectivity of key brain regions involved in mood regulation, reduce neuro-inflammatory sensitization, modulate the autonomic nervous system, and regulate hippocampal neurogenesis. Finally, we discuss common challenges of the intervention and possible ways to address them. Specifically, we pose developing a simplified and tailored Tai Chi protocol for patients with depression, comparatively investigating Tai Chi with other mind-body interventions such as yoga and Baduanjin, and developing new mind-body interventions that merge the advantages of multiple mind-body exercises.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.