Evidence map›Paper›PMID 31031663›Full record

ArticleFrontiers in psychiatry2019

Treating Depression With Tai Chi: State of the Art and Future Perspectives.

Jian Kong, Georgia Wilson, Joel Park, Kaycie Pereira, Courtney Walpole, Albert Yeung

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 7 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 7 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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  6. Stress management interventions for adults with heart failure: Systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
    Pooled it
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  9. Mild Cognitive Impairment and Suicidal Ideation Among Adults Aged 65 Years or Older From Low- and Middle-Income Countries.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
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  19. TraditionalFrontiers in cardiovascular medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jian KongPsychiatry Department, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.
Georgia WilsonPsychiatry Department, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.
Joel ParkPsychiatry Department, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.
Kaycie PereiraPsychiatry Department, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.
Courtney WalpolePsychiatry Department, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.
Albert YeungDepression Clinical and Research Program, Massachusetts General Hospital, Boston, MA, United States.
Massachusetts General Hospital · USHarvard University · US

Funding

Treatment of chronic low back pain with transcutaneous auricular vagus nerve stimulationR34DA046635 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI KONG, JIAN · 2019 to 2021
$766k
Neural dynamics of directly and indirectly conditioned placebo/nocebo effectR21AT008707 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI KONG, JIAN · 2016 to 2017
$479k
NCCIH NIH HHS R21 AT008707NIDA NIH HHS R34 DA046635
6 · The paper itself

Abstract

Major depressive disorder (MDD) is one of the most prevalent mental illnesses in America. Current treatments for MDD are unsatisfactory given high non-response rates, high relapse rates, and undesirable side effects. Accumulating evidence suggests that Tai Chi, a popular mind-body intervention that originated as a martial art, can significantly regulate emotion and relieve the symptoms of mood disorders. In addition, the availability of instructional videos and the development of more simplified and less structured Tai Chi has made it a promising low-intensity mind-body exercise. In this article, we first examine a number of clinical trials that implemented Tai Chi as a treatment for depression. Then, we explore several mechanisms by which Tai Chi may alleviate depressive symptoms, hypothesizing that the intervention may modulate the activity and connectivity of key brain regions involved in mood regulation, reduce neuro-inflammatory sensitization, modulate the autonomic nervous system, and regulate hippocampal neurogenesis. Finally, we discuss common challenges of the intervention and possible ways to address them. Specifically, we pose developing a simplified and tailored Tai Chi protocol for patients with depression, comparatively investigating Tai Chi with other mind-body interventions such as yoga and Baduanjin, and developing new mind-body interventions that merge the advantages of multiple mind-body exercises.

Indexed as

anti-inflammationbrain networkdepressionmajor depressive disordermind–body interventionTai Chi

Identifiers

PMID31031663
PMCPMC6474282
OpenAlexW2936987162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.