Evidence map›Paper›PMID 31031639›Full record

ArticleFrontiers in physiology2019

Gross Motor Skills Training Leads to Increased Brain-Derived Neurotrophic Factor Levels in Healthy Older Adults: A Pilot Study.

Catherine-Alexandra Grégoire, Nicolas Berryman, Florence St-Onge, Thien Tuong Minh Vu, Laurent Bosquet, Nathalie Arbour, Louis Bherer

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07701317 (Effects of Exergame and Gross Motor-cognitive Training on Executive Functions and Gross Motor Skills in Self-sufficient Older Adults), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07701317 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Exergame and Gross Motor-cognitive Training on Executive Functions and Gross Motor Skills in Self-sufficient Older Adults: a Randomized Controlled Trial With 20-week Follow-up.

TypeinterventionalSponsorUniversity of PalermoRan2025 to 2026Enrolled108ConditionsActive Aging Individuals Aged 60 and OverArmsallenamento tramite Exergame, Gross motor-cognitive training
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Modulation of premotor cortex response to sequence motor learning during escitalopram intake.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Trial
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  4. Review
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  6. Synergistic Effects of Cognitive Training and Physical Exercise on Dual-Task Performance in Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
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  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Catherine-Alexandra GrégoireMontreal Heart Institute, Montreal, QC, Canada.
Nicolas BerrymanCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada.
Florence St-OngeCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada.
Thien Tuong Minh VuDepartment of Medicine, Centre Hospitalier de l'Université de Montréal, Service de Gériatrie, Montreal, QC, Canada.
Laurent BosquetLaboratory MOVE (EA 6314), Faculty of Sport Sciences, Université de Poitiers, Poitiers, France.
Nathalie ArbourDepartment of Neuroscience, Université de Montréal, CRCHUM, Montreal, QC, Canada.
Louis BhererMontreal Heart Institute, Montreal, QC, Canada.
Université de Montréal · CABishop's University · CACentre Hospitalier de l’Université de Montréal · CAConcordia University · CAInstitut Universitaire de Gériatrie de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise is recognized as a promising approach to counteract aging-associated declines in cognitive functions. However, the exact molecular pathways involved remain unclear. Aerobic training interventions and improvements in peak oxygen uptake (VO

Indexed as

agingbiomarkerscognitionexercisefitness

Identifiers

PMID31031639
PMCPMC6473056
OpenAlexW2936014450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.