ArticleFrontiers in physiology2019
Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos).Acta physiologica (Oxford, England) · 2026Article
- Intestinal bacteria trigger a hibernation-like state in homotherms via the gut-brain axis.NPJ biofilms and microbiomes · 2025Article
- Unsaturated fat alters clock phosphorylation to align rhythms to the season in mice.Science (New York, N.Y.) · 2025Article
- Analysis of Lipid Metabolism in Adipose Tissue and Liver of Chinese Soft-Shelled TurtleInternational journal of molecular sciences · 2024Article
- Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation.eLife · 2024Article
- Lipidomic and transcriptomic profiles provide new insights into the triacylglycerol and glucose handling capacities of the Arctic fox.Frontiers in veterinary science · 2024Article
- A general overview of the multifactorial adaptation to cold: biochemical mechanisms and strategies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Review
- Sepsis-Associated Muscle Wasting: A Comprehensive Review from Bench to Bedside.International journal of molecular sciences · 2023Review
- Elevated plasma phospholipid n-3 docosapentaenoic acid concentrations during hibernation.PloS one · 2023Article
- Article
- Big boned: How fat storage and other adaptations influenced large theropod foraging ecology.PloS one · 2023Article
- Article
- Molecular Liver Fingerprint Reflects the Seasonal Physiology of the Grey Mouse Lemur (International journal of molecular sciences · 2022Article
- Hibernating brown bears are protected against atherogenic dyslipidemia.Scientific reports · 2021Article
- Cardiomyocyte Protection by Hibernating Brown Bear Serum: Toward the Identification of New Protective Molecules Against Myocardial Infarction.Frontiers in cardiovascular medicine · 2021Article
- Body Protein Sparing in Hibernators: A Source for Biomedical Innovation.Frontiers in physiology · 2021Review
- Specific shifts in the endocannabinoid system in hibernating brown bears.Frontiers in zoology · 2020Article
- Denning in brown bears.Ecology and evolution · 2020Review
- Regulation of Peroxisome Proliferator-Activated Receptor Pathway During Torpor in the Garden Dormouse,Frontiers in physiology · 2020Article
- Proteomic and Transcriptomic Changes in Hibernating Grizzly Bears Reveal Metabolic and Signaling Pathways that Protect against Muscle Atrophy.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 4 countries.
Funding
Abstract
Prior to winter, heterotherms retain polyunsaturated fatty acids ("PUFA"), resulting in enhanced energy savings during hibernation, through deeper and longer torpor bouts. Hibernating bears exhibit a less dramatic reduction (2-5°C) in body temperature, but lower their metabolism to a degree close to that of small hibernators. We determined the lipid composition, via lipidomics, in skeletal muscle and white adipose tissues ("WAT"), to assess lipid retention, and in blood plasma, to reflect lipid trafficking, of winter hibernating and summer active wild Scandinavian brown bears (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.