Evidence map›Paper›PMID 31031616›Full record

ArticleFrontiers in aging neuroscience2019

Cerebrovascular Resistance in Healthy Aging and Mild Cognitive Impairment.

Larissa McKetton, Melanie Cohn, David F Tang-Wai, Olivia Sobczyk, James Duffin, Kenneth R Holmes, Julien Poublanc, Kevin Sam, Adrian P Crawley, Lashmi Venkatraghavan and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Larissa McKettonJoint Department of Medical Imaging, University Health Network (UHN), Toronto, ON, Canada.
Melanie CohnKrembil Brain Institute, University Health Network (UHN), Toronto, ON, Canada.
David F Tang-WaiKrembil Brain Institute, University Health Network (UHN), Toronto, ON, Canada.
Olivia SobczykJoint Department of Medical Imaging, University Health Network (UHN), Toronto, ON, Canada.
James DuffinDepartment of Physiology, University of Toronto, Toronto, ON, Canada.
Kenneth R HolmesInstitute of Medical Science, University of Toronto, Toronto, ON, Canada.
Julien PoublancJoint Department of Medical Imaging, University Health Network (UHN), Toronto, ON, Canada.
Kevin SamRussell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Adrian P CrawleyJoint Department of Medical Imaging, University Health Network (UHN), Toronto, ON, Canada.
Lashmi VenkatraghavanDepartment of Anaesthesia and Pain Management, University Health Network (UHN), Toronto, ON, Canada.
Joseph A FisherJoint Department of Medical Imaging, University Health Network (UHN), Toronto, ON, Canada.
David J MikulisJoint Department of Medical Imaging, University Health Network (UHN), Toronto, ON, Canada.
University Health Network · CAUniversity of Toronto · CAJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measures of cerebrovascular reactivity (CVR) are used to judge the health of the brain vasculature. In this study, we report the use of several different analyses of blood oxygen dependent (BOLD) fMRI responses to CO

Indexed as

agingcarbon dioxidecerebrovascular reactivity (CVR)cerebrovascular resistancemild cognitive impairment (MCI)vascular health

Identifiers

PMID31031616
PMCPMC6474328
OpenAlexW2936411159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.