Evidence map›Paper›PMID 31031593›Full record

ArticleFrontiers in cellular neuroscience2019

Electrophysiological Properties of Adult Zebrafish Oligodendrocyte Progenitor Cells.

Vasiliki Tsata, Volker Kroehne, Susanne Reinhardt, Ali El-Armouche, Michael Brand, Michael Wagner, Michell M Reimer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Towards Zebrafish Models of CNS Channelopathies.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Vasiliki TsataCenter for Regenerative Therapies TU Dresden (CRTD) and Center for Molecular and Cellular Bioengineering (CMCB), Technische Universitaet, Dresden, Germany.
Volker KroehneCenter for Regenerative Therapies TU Dresden (CRTD) and Center for Molecular and Cellular Bioengineering (CMCB), Technische Universitaet, Dresden, Germany.
Susanne ReinhardtDresden Genome Center, Center for Regenerative Therapies TU Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), Technische Universitaet Dresden, Dresden, Germany.
Ali El-ArmoucheDepartment of Pharmacology and Toxicology, Technische Universitaet Dresden, Dresden, Germany.
Michael BrandCenter for Regenerative Therapies TU Dresden (CRTD) and Center for Molecular and Cellular Bioengineering (CMCB), Technische Universitaet, Dresden, Germany.
Michael WagnerDepartment of Pharmacology and Toxicology, Technische Universitaet Dresden, Dresden, Germany.
Michell M ReimerCenter for Regenerative Therapies TU Dresden (CRTD) and Center for Molecular and Cellular Bioengineering (CMCB), Technische Universitaet, Dresden, Germany.
Technische Universität Dresden · DECenter for Systems Biology Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low remyelination efficiency after spinal cord injury (SCI) is a major restraint to successful axonal and functional regeneration in mammals. In contrast, adult zebrafish can: (i) regenerate oligodendrocytes and myelin sheaths within 2 weeks post lesion; (ii) re-grow axonal projections across the lesion site and (iii) recover locomotor function within 6 weeks after spinal cord transection. However, little is known about the intrinsic properties of oligodendrocyte progenitor cells (OPCs), the remyelinating cells of the central nervous system (CNS). Here, we demonstrate that purified OPCs from the adult zebrafish spinal cord are electrically active. They functionally express voltage-gated K

Indexed as

adult zebrafishelectrophysiologyglutamate receptorsin vitroion channelsoligodendrocyte progenitor cellspatch-clampspinal cord

Identifiers

PMID31031593
PMCPMC6473327
OpenAlexW2936266523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.