Evidence map›Paper›PMID 31031590›Full record

ArticleFrontiers in molecular neuroscience2019

Combinational Treatment of Bioscaffolds and Extracellular Vesicles in Spinal Cord Injury.

Xizhi Wang, Benson O A Botchway, Yong Zhang, Jiaying Yuan, Xuehong Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

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  12. Exosomes combined with biomaterials in the treatment of spinal cord injury.Frontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xizhi WangDepartment of Histology and Embryology, Medical College, Shaoxing University, Zhejiang, China.
Benson O A BotchwayInstitute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, China.
Yong ZhangDepartment of Histology and Embryology, Medical College, Shaoxing University, Zhejiang, China.
Jiaying YuanDepartment of Histology and Embryology, Medical College, Shaoxing University, Zhejiang, China.
Xuehong LiuDepartment of Histology and Embryology, Medical College, Shaoxing University, Zhejiang, China.
Shaoxing University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury (SCI) can result in an irreversible disability due to loss of sensorimotor function below the lesion. Presently, clinical treatments for SCI mainly include surgery, drugs and postoperative rehabilitation. The prospective roles of bioscaffolds and exosomes in several neurological diseases have been reported. Bioscaffolds can reconnect lesion gaps as well as transport cells and bioactive factors, which in turn can improve axonal and functional regeneration. Herein, we explicate the respective roles of bioscaffolds and exosomes in SCI, and elucidate on the usage of combinational therapy involving bioscaffolds and extracellular vesicles (EVs) in improving SCI.

Indexed as

bioscaffoldsextracellular vesiclesfunctional and axonal regenerationneuronal damagespinal cord injurystem cell therapy

Identifiers

PMID31031590
PMCPMC6474389
OpenAlexW2936412613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.