ArticleFrontiers in neuroscience2019
Cerebellar Lobules Optimal Stimulation (CLOS): A Computational Pipeline to Optimize Cerebellar Lobule-Specific Electric Field Distribution.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Outcome measures for electric field modeling in tES and TMS: A systematic review and large-scale modeling study.NeuroImage · 2023Pooled it
- Bibliometric and visualised analysis on non-invasive cerebellar stimulation from 1995 to 2021.Frontiers in neuroscience · 2023Pooled it
- Effects of HD-tDCS targeting prefrontal cortex, cerebellum, and motor cortex on dual-task gait in older adults.Scientific reports · 2025Trial
- Modulating mental state recognition by anodal tDCS over the cerebellum.Scientific reports · 2022Trial
- Investigating the feasibility of cerebellar transcranial direct current stimulation to facilitate post-stroke overground gait performance in chronic stroke: a partial least-squares regression approach.Journal of neuroengineering and rehabilitation · 2021Trial
- Polarity-dependent modulation of sensory circuits by cerebellar tDCS: local and distant effects.Scientific reports · 2026Article
- Recognising Emotions from the Voice: A tDCS and fNIRS Double-Blind Study on the Role of the Cerebellum in Emotional Prosody.Brain sciences · 2025Article
- Polarity-dependent modulation of sensory circuits by cerebellar tDCS: local and distant effects.bioRxiv : the preprint server for biology · 2025Article
- Platform Technology for Extended Reality Biofeedback Training Under Operant Conditioning for Functional Limb Weakness: Protocol for the Coproduction of an at-Home Solution (React2Home).JMIR research protocols · 2025Article
- Neurocomputational Mechanisms of Sense of Agency: Literature Review for Integrating Predictive Coding and Adaptive Control in Human-Machine Interfaces.Brain sciences · 2025Review
- Time Dependent Effects of Cerebellar tDCS on Cerebello-cortical Connectivity Networks in Young Adults.Cerebellum (London, England) · 2025Article
- Investigating Cerebello-Frontal Circuits Associated with Emotional Prosody: A Double-Blind tDCS and fNIRS study.Cerebellum (London, England) · 2024Article
- Perspectives on Optimized Transcranial Electrical Stimulation Based on Spatial Electric Field Modeling in Humans.Journal of clinical medicine · 2024Review
- Consensus Paper: Cerebellum and Ageing.Cerebellum (London, England) · 2024Review
- Population-level insights into temporal interference for focused deep brain neuromodulation.Frontiers in human neuroscience · 2024Article
- Neuronavigated Cerebellar 50 Hz tACS: Attenuation of Stimulation Effects by Motor Sequence Learning.Biomedicines · 2023Article
- Electric Fields Induced in the Brain by Transcranial Electric Stimulation: A Review of In Vivo Recordings.Biomedicines · 2022Review
- A Brief History of Cerebellar Neurostimulation.Cerebellum (London, England) · 2022Review
- New Horizons on Non-invasive Brain Stimulation of the Social and Affective Cerebellum.Cerebellum (London, England) · 2022Review
- Portable Neuroimaging-Guided Noninvasive Brain Stimulation of the Cortico-Cerebello-Thalamo-Cortical Loop-Hypothesis and Theory in Cannabis Use Disorder.Brain sciences · 2022Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCerebellar transcranial direct current stimulation (ctDCS) is challenging due to the complexity of the cerebellar structure which is reflected by the well-known variability in ctDCS effects. Therefore, our objective is to present a freely available computational modeling pipeline for cerebellar lobules' optimal stimulation (CLOS).
methodsCLOS can optimize lobule-specific electric field distribution following finite element analysis (FEA) using freely available computational modeling pipelines. We modeled published ctDCS montages with 5 cm × 5 cm anode placed 3 cm lateral to inion, and the same sized cathode was placed on the: (1) contralateral supra-orbital area (called Manto montage), and (2) buccinators muscle (called Celnik montage). Also, a published (3) 4×1 HD-ctDCS electrode montage was modeled. We also investigated the effects of the subject-specific head model versus Colin 27 average head model on lobule-specific electric field distribution. Three-way analysis of variance (ANOVA) was used to determine the effects of lobules, montage, and head model on the electric field distribution. The differences in lobule-specific electric field distribution across different freely available computational pipelines were also evaluated using subject-specific head model. We also presented an application of our computational pipeline to optimize a ctDCS electrode montage to deliver peak electric field at the cerebellar lobules VII-IX related to ankle function.
resultsEta-squared effect size after three-way ANOVA for electric field strength was 0.05 for lobule, 0.00 for montage, 0.04 for the head model, 0.01 for lobule DISCUSSION: Our freely available CLOS pipeline can be leveraged to optimize electromagnetic stimulation to target cerebellar lobules related to different cognitive and motor functions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.