Evidence map›Paper›PMID 3103129›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1987

Gene encoding cytoskeletal proteins in Drosophila rhabdomeres.

H Matsumoto, K Isono, Q Pye, W L Pak

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Retinophilin is a light-regulated phosphoprotein required to suppress photoreceptor dark noise in Drosophila.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010
    Article
  6. Article
  7. Phototransduction and retinal degeneration in Drosophila.Pflugers Archiv : European journal of physiology · 2007
    Review
  8. Article
  9. Article
  10. From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  11. Modulation of the light response by cAMP in Drosophila photoreceptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999
    Article
  12. Requirement for the NINAC kinase/myosin for stable termination of the visual cascade.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998
    Article
  13. Calmodulin regulation of light adaptation and store-operated dark current in Drosophila photoreceptors.Proceedings of the National Academy of Sciences of the United States of America · 1997
    Article
  14. Article
  15. Article
  16. Article
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  18. Isolation and structure of an arrestin gene from Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 1990
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

H Matsumoto
K Isono
Q Pye
W L Pak
Purdue University West Lafayette · US

Funding

MOLECULAR GENETIC DISSECTION OF PHOTORECEPTOR FUNCTIONR01EY000033 · NEI · PURDUE UNIVERSITY WEST LAFAYETTE · PI PAK, WILLIAM L · 1985 to 2008
$3.7M
Molecular Genetic Dissection of Photoreceptor FunctionR56EY000033 · NEI · PURDUE UNIVERSITY · PI PAK, WILLIAM L · 2009 to 2009
$343k
INTERDISCIPLINARY STUDIES OF VISUAL PROCESSESP30EY002723 · NEI · PURDUE UNIVERSITY WEST LAFAYETTE · PI PAK, WILLIAM L · 1985 to 1989
–
MOLECULAR GENETIC DISSECTION OF PHOTORECEPTOR FUNCTIONR37EY000033 · NEI · PURDUE UNIVERSITY WEST LAFAYETTE · PI PAK, WILLIAM L · 1990 to 1999
–
NEI NIH HHS EY00033NEI NIH HHS EY02723
6 · The paper itself

Abstract

The ninaC gene is one of eight nina (neither inactivation nor afterpotential) genes identified from mutations that drastically reduce the amount of rhodopsin in the compound eye of Drosophila melanogaster. The gene has been cytogenetically localized to the 27E-28B region of the second chromosome. NaDodSO4/PAGE analysis of eye proteins of flies carrying one, two, or three copies of the ninaC region shows that two eye-specific proteins of molecular weight 170,000 and 130,000 display a strong dependence on the dosage of the ninaC gene, although the dependence is evident only when the dosage is decreased and not when it is increased. All mutations in the ninaC gene studied to date have pronounced effects on these two polypeptides. These results suggest that the ninaC locus encodes these two polypeptides. Ultrastructural studies show that the polypeptides encoded by ninaC are very likely to be important components of the cytoskeletal structure of rhabdomeral microvilli.

Indexed as

GenesGenetic CodeCytogeneticsCytoskeletal ProteinsDrosophila melanogasterElectrophysiologyGeneticsGenetic TechniquesMicroscopy, ElectronOrganoidsPhotoreceptor CellsCytoskeletal Proteins

Identifiers

PMID3103129
PMCPMC304346
OpenAlexW2014893784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.