ArticleCell2019
Marine DNA Viral Macro- and Microdiversity from Pole to Pole.
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Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 455 papers.
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455citing papers in PubMed
80.9field-weighted citation impact, top 1% of its field
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Who cites it
455 citing papers in PubMed, 884 citations in OpenAlex.
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- Hawaiian Geothermal Fumaroles Contain Diverse and Novel Viruses.bioRxiv : the preprint server for biology · 2026Article
- Patterns and drivers of macro- and micro-diversity of mudflat intertidal archaeomes along the Chinese coasts.mSystems · 2026Article
395 more citing papers are in PubMed but not listed here.
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Authors and funding
34 authors at 20 institutions in 11 countries.
Ann C GregoryDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Ahmed A ZayedDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Nádia Conceição-NetoDepartment of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Viral Metagenomics, KU Leuven-University of Leuven, Leuven, Belgium; Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven-University of Leuven, Leuven, Belgium.
Ben TempertonSchool of Biosciences, University of Exeter, Exeter, UK.
Ben BolducDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Adriana AlbertiGénomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91057 Evry, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Mathieu ArdynaSorbonne Université, CNRS, Laboratoire d'Océanographie de Villefanche, LOV, 06230 Villefranche-sur-mer, France.
Ksenia ArkhipovaTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, the Netherlands.
Margaux CarmichaelSorbonne Université, CNRS, Station Biologique de Roscoff, AD2M ECOMAP, 29680 Roscoff, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Corinne CruaudCEA-Institut de Biologie François Jacob, Genoscope, Evry 91057, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Céline DimierSorbonne Université, CNRS, Laboratoire d'Océanographie de Villefanche, LOV, 06230 Villefranche-sur-mer, France; Institut de Biologie de l'ENS (IBENS), Département de biologie, École normale supérieure, CNRS, INSERM, Université PSL, 75005 Paris, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Guillermo Domínguez-HuertaDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Joannie FerlandDépartement de biologie, Québec Océan and Takuvik Joint International Laboratory (UMI 3376), Université Laval (Canada)-CNRS (France), Université Laval, Québec, QC G1V 0A6, Canada.
Stefanie KandelsStructural and Computational Biology, European Molecular Biology Laboratory, 69117 Heidelberg, Germany; Directors' Research, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
Yunxiao LiuDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Claudie MarecDépartement de biologie, Québec Océan and Takuvik Joint International Laboratory (UMI 3376), Université Laval (Canada)-CNRS (France), Université Laval, Québec, QC G1V 0A6, Canada.
Stéphane PesantPANGAEA, Data Publisher for Earth and Environmental Science, University of Bremen, 28359 Bremen, Germany; MARUM, Bremen University, 28359 Bremen, Germany.
Marc PicheralSorbonne Université, CNRS, Laboratoire d'Océanographie de Villefanche, LOV, 06230 Villefranche-sur-mer, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Sergey PisarevShirshov Institute of Oceanology of Russian Academy of Sciences, 36 Nakhimovsky prosp, 117997 Moscow, Russia.
Julie PoulainGénomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91057 Evry, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Jean-Éric TremblayDépartement de biologie, Québec Océan and Takuvik Joint International Laboratory (UMI 3376), Université Laval (Canada)-CNRS (France), Université Laval, Québec, QC G1V 0A6, Canada.
Dean VikDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Tara Oceans Coordinators
Marcel BabinDépartement de biologie, Québec Océan and Takuvik Joint International Laboratory (UMI 3376), Université Laval (Canada)-CNRS (France), Université Laval, Québec, QC G1V 0A6, Canada.
Chris BowlerInstitut de Biologie de l'ENS (IBENS), Département de biologie, École normale supérieure, CNRS, INSERM, Université PSL, 75005 Paris, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Alexander I CulleyDépartement de biochimie, microbiologie et bio-informatique, Université Laval, Québec, QC G1V 0A6, Canada.
Colomban de VargasSorbonne Université, CNRS, Station Biologique de Roscoff, AD2M ECOMAP, 29680 Roscoff, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Bas E DutilhTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, the Netherlands; Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre, Nijmegen, the Netherlands.
Daniele IudiconeStazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy.
Lee Karp-BossSchool of Marine Sciences, University of Maine, Orono, ME, USA.
Simon RouxDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Shinichi SunagawaDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, 8093 Zurich, Switzerland.
Patrick WinckerGénomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91057 Evry, France; Research Federation for the study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 3 rue Michel-Ange, 75016 Paris, France.
Matthew B SullivanDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA; Department of Civil, Environmental and Geodetic Engineering, The Ohio State University, Columbus, OH 43210, USA. Electronic address: mbsulli@gmail.com.
Centre National de la Recherche Scientifique · FRThe Ohio State University · USStazione Zoologica Anton Dohrn · ITUniversity of Bremen · DEGenoscope · FRLaboratoire d’Océanographie de Villefranche · FRSIB Swiss Institute of Bioinformatics · CHState Library of Ohio · USUniversité Laval · CABiologie Intégrative des Organismes Marins · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRÉcole Normale Supérieure - PSL · FREuropean Molecular Biology Laboratory · DEEuropean Molecular Biology Laboratory · FREuropean Molecular Biology Laboratory · DEGénomique Métabolique du Genoscope · FRInstitut de Ciències del Mar · ESInstitute of Oceanology. PP Shirshov Russian Academy of Sciences · RUInstitut Océanographique · FRMassachusetts Institute of Technology · US
Funding
Interdisciplinary Program in Microbe-Host BiologyT32AI112542 · NIAID · OHIO STATE UNIVERSITY · PI JUSTICE, SHERYL S, WOZNIAK, DANIEL J · 2014 to 2018
$644kNIAID NIH HHS T32 AI112542
Abstract
Microbes drive most ecosystems and are modulated by viruses that impact their lifespan, gene flow, and metabolic outputs. However, ecosystem-level impacts of viral community diversity remain difficult to assess due to classification issues and few reference genomes. Here, we establish an ∼12-fold expanded global ocean DNA virome dataset of 195,728 viral populations, now including the Arctic Ocean, and validate that these populations form discrete genotypic clusters. Meta-community analyses revealed five ecological zones throughout the global ocean, including two distinct Arctic regions. Across the zones, local and global patterns and drivers in viral community diversity were established for both macrodiversity (inter-population diversity) and microdiversity (intra-population genetic variation). These patterns sometimes, but not always, paralleled those from macro-organisms and revealed temperate and tropical surface waters and the Arctic as biodiversity hotspots and mechanistic hypotheses to explain them. Such further understanding of ocean viruses is critical for broader inclusion in ecosystem models.
Indexed as
BiodiversityMetagenomeWater MicrobiologyAquatic OrganismsDNA, ViralDNA VirusesDNA, Viralcommunity ecologydiversity gradientsmarine biologymetagenomicspopulation ecologyspeciesviruses
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