Evidence map›Paper›PMID 31030903›Full record

ArticleBrazilian journal of anesthesiology (Elsevier)

[Minimum effective volume of bupivacaine 0.5% for ultrasound-guided retroclavicular approach to infraclavicular brachial plexus block].

Ali Sait Kavakli, Nilgun Kavrut Ozturk, Ulku Arslan

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Article in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ali Sait KavakliUniversity of Health Sciences, Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation, Antalya, Turquia. Electronic address: alisaitkavakli@hotmail.com.
Nilgun Kavrut OzturkUniversity of Health Sciences, Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation, Antalya, Turquia.
Ulku ArslanUniversity of Health Sciences, Antalya Training and Research Hospital, Department of Anesthesiology and Reanimation, Antalya, Turquia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe current study aimed to determine the minimum effective volume (MEV) of bupivacaine 0.5% in 50% of patients for an ultrasound-guided retroclavicular approach to infraclavicular brachial plexus block.

methodsA total of 25 adult patients who were scheduled for upper limb surgery received an ultrasound-guided retroclavicular approach to infraclavicular brachial plexus block with bupivacaine 0.5%. The needle insertion point was posterior to the clavicle and the needle was advanced from cephalad to caudal. Block success was defined as a composite score of 14 at 30min after local anesthetic (LA) injection. The minimum effective volume in 50% of patients was determined using the Dixon-Massey up-and-down staircase method. Minimum effective volume for a successful block in 95% of the patients was also calculated using logistic regression and probit transformation.

resultsThe minimum effective volume of bupivacaine 0.5% resulting in successful block in 50% of patients (MEV50) according to the up-and-down staircase method was found to be 9.6mL (95% confidence interval (CI), 5.7-13.4). The calculated minimum effective volume required for a successful block in 95% of patients (MEV95) using the probit transformation and logistic regression analysis was 23.2mL (95% CI, 18.8-36.7).

conclusionsThe MEV50 of bupivacaine 0.5% for US-guided retroclavicular approach to infraclavicular brachial plexus block was 9.6mL and the calculated MEV95 was 23.2mL. Future studies are required for infraclavicular brachial plexus block with different approaches, other LA agents and different concentrations of bupivacaine.

Indexed as

AdultAnesthetics, LocalBrachial Plexus BlockBupivacaineDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedUltrasonography, InterventionalUpper ExtremityAnesthetics, LocalBupivacaineBloqueio do plexo braquial por via infraclavicularBloqueio retroclavicularGuiado por ultrassomInfraclavicular brachial plexus blockMinimum effective volumeRetroclavicular blockUltrasound guidedVolume mínimo efetivo

Identifiers

PMID31030903
PMCPMC9391849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.