Evidence map›Paper›PMID 31030860›Full record

ReviewThe Canadian journal of cardiology2019

Evolution of Blood Pressure Clinical Practice Guidelines: A Personal Perspective.

Paul K Whelton

Open access · greenAbstract readHistorical ArticleReview
In one paragraph

Review in The Canadian journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Evolution in the targets for blood pressure treatment.Current opinion in nephrology and hypertension · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. GPs' mindlines on deprescribing antihypertensives in older patients with multimorbidity: a qualitative study in English general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Paul K WheltonDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA. Electronic address: pkwhelton@gmail.com.
Tulane University · US

Funding

Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Ning Liu · 2016 to 2026
$25.3M
NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

Before the second half of the 20th century, most clinical decision making was based on expert opinion. By the 1960s, experience in actuarial and research cohort studies had provided strong evidence that blood pressure was an important risk factor for cardiovascular disease. The landmark 1967 and 1970 Veterans Administration Cooperative Study trials confirmed the value of antihypertensive drug therapy in preventing stroke, myocardial infarction, and heart failure in adults with high levels of diastolic blood pressure. They also provided an impetus to develop the first blood-pressure-related clinical practice guideline in 1977. In subsequent years, more structured and comprehensive blood-pressure guidelines have evolved to become a major resource in clinical and public health practice. Despite some limitations, these guidelines provide useful evidence-based guidance for diagnosis and management of high blood pressure. The core advice in most of the current comprehensive blood pressure guidelines is more similar than different. Modelling studies suggest that better adherence to guideline recommendations would result in a lower average blood pressure and substantial improvement in public health.

Indexed as

Blood PressurePractice Guidelines as TopicAntihypertensive AgentsCardiologyCardiovascular DiseasesHistory, 20th CenturyHistory, 21st CenturyHumansHypertensionRisk FactorsAntihypertensive Agents

Identifiers

PMID31030860
PMCPMC6494109
OpenAlexW2915385987

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.