ReviewProgress in molecular biology and translational science2019
The structures and biological functions of polysaccharides from traditional Chinese herbs.
Review in Progress in molecular biology and translational science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers, 3 of them syntheses that pooled it.
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Who cites it
143 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of tiger milk mushroom (Lignosus rhinocerus) on asthma: a systematic review.BMC pulmonary medicine · 2026Pooled it
- Effects of traditional Chinese medicine polysaccharides on rheumatoid arthritis through gut microbiota modulation: a systematic review in animal models.Frontiers in immunology · 2026Pooled it
- Extraction, Purification, Structural Characteristics, Biological Activities, and Applications of the Polysaccharides fromMolecules (Basel, Switzerland) · 2023Pooled it
- Review
- Extraction, Purification, Structural Characterization, Biological Activities and Applications in Food of Polysaccharides fromFoods (Basel, Switzerland) · 2026Review
- Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4.Phytotherapy research : PTR · 2026Article
- Mechanistic insights into the roles of astragalosides andOncology reports · 2026Review
- The Protective Effects and Underlying Mechanisms ofAnimals : an open access journal from MDPI · 2026Article
- Integrative analyses of the transcriptome and metabolome of Huzhang (Pinellia pedatisecta Schott) uncover the molecular genetic basis of its medicinal properties.BMC genomics · 2026Article
- Structural Characterization and Antioxidant Activity of Polysaccharides From Indigo NaturalisFood science & nutrition · 2026Article
- Comparative Study on the In Vitro Fermentation Characteristics of Three Plant-Derived Polysaccharides with Different Structural Compositions.Foods (Basel, Switzerland) · 2026Article
- Targeting mitochondrial dysfunction with traditional Chinese medicine for inflammatory bowel disease: a comprehensive review.Frontiers in pharmacology · 2026Review
- Molecular mechanisms of polysaccharide components of kidney-tonifying traditional Chinese medicine in regulating osteoporosis.Frontiers in pharmacology · 2026Review
- Microbiota-metabolites interaction associated with glycemic improvement following a dietary herbal intervention in type 2 diabetes.Frontiers in nutrition · 2026Article
- Review
- DietaryVeterinary world · 2026Article
- Research advances in red ginseng polysaccharides: preparation, structural characteristics and immunomodulatory effect.Frontiers in pharmacology · 2026Review
- Article
- Comparison of Extraction, Isolation, Purification, Structural Characterization and Immunomodulatory Activity of Polysaccharides from Two Species ofMolecules (Basel, Switzerland) · 2025Article
- Review
83 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most of traditional Chinese medicine substances come from herbal plants. The medicinal quality of herbal plants varies with the locations of cultivation, the parts of the herb collected, the season of the herb collected, and the herb processing method. Polysaccharides are major components of the herb plants and their biosynthesis is partly controlled by the genes but mostly influenced by the availability of the nutrition and determined by the various environmental factors. In recent decades, polysaccharides isolated from different kinds of Chinese herbs have received much attention due to their important biological activities, such as anti-tumor, anti-oxidant, anti-diabetic, radiation protecting, antiviral, hypolipidemic, and immunomodulatory activities. Interestingly, different batches of the same herb can obtain different polysaccharide fractions with subtle differences in molecular weight, monosaccharide compositions, glycosidic linkages, and biological functions. Even with these variations, a large number of bioactive polysaccharides from different kinds of traditional Chinese herbs have been purified, characterized, and reported. This review provides a comprehensive summary of the latest polysaccharide extraction methods and the strategies used for monosaccharide compositional analysis plus polysaccharide structural characterization. Most importantly, the reported chemical characteristics and biological activities of the polysaccharides from the famous traditional Chinese herbs including Astragalus membranaceus, Ginseng, Lycium barbarum, Angelica sinensis, Cordyceps sinensis, and Ophiopogon japonicus will be reviewed and discussed. The published studies provide evidence that polysaccharides from traditional Chinese herbs play an important role in their medical applications, which forms the basis for future research, development, and application of these polysaccharides as functional foods and therapeutics in modern medicine.
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