Evidence map›Paper›PMID 31030617›Full record

ArticleJournal of the American Heart Association2019

Regulator of G Protein Signaling 2 Facilitates Uterine Artery Adaptation During Pregnancy in Mice.

Jennifer N Koch, Shelby A Dahlen, Elizabeth A Owens, Patrick Osei-Owusu

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. G protein regulation by RGS proteins in the pathophysiology of dilated cardiomyopathy.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  3. Anti-angiogenic mechanisms and serotonergic dysfunction in the Rgs2 knockout model for the study of psycho-obstetric risk.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jennifer N Koch1 Department of Pharmacology and Physiology Drexel University College of Medicine Philadelphia PA.
Shelby A Dahlen1 Department of Pharmacology and Physiology Drexel University College of Medicine Philadelphia PA.
Elizabeth A Owens1 Department of Pharmacology and Physiology Drexel University College of Medicine Philadelphia PA.
Patrick Osei-Owusu1 Department of Pharmacology and Physiology Drexel University College of Medicine Philadelphia PA.
Drexel University · US

Funding

In Vivo Mechanisms of Integrated G protein Signaling Regulation by RGS ProteinsR01HL139754 · NHLBI · DREXEL UNIVERSITY · PI OSEI-OWUSU, PATRICK · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL139754
6 · The paper itself

Abstract

Background Decreased uterine blood flow is known to contribute to pregnancy complications such as gestational hypertension and preeclampsia. Previously, we showed that the loss of regulator of G protein signaling 2 ( RGS 2), a GTP ase activating protein for G

Indexed as

AnimalsFemaleMiceMice, KnockoutPregnancyPregnancy, AnimalRegional Blood FlowRGS ProteinsRNA, MessengerUltrasonography, DopplerUterine ArteryVascular RemodelingVascular ResistanceRgs2 protein, mouseRGS4 proteinRgs5 protein, mouseRGS ProteinsRNA, Messengeranimal modelG protein–coupled receptor signalingknockout micepregnancy and postpartumRGS proteinsuterine blood flowvascular reactivity

Identifiers

PMID31030617
PMCPMC6512123
OpenAlexW2941389670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.