Evidence map›Paper›PMID 31030465›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2019

Availability of Essential Medicines for Pediatric Oncology in Armenia

Tamara Simonyan, Ruzanna Papyan, Samvel Danielyan, Lilit Sargsyan, Varduhi Grigoryan, Hakob Topchyan, Arpina Azaryan, Armen Tananyan, Armen Muradyan, Gevorg Tamamyan

Open access · goldAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Tamara SimonyanAmerican University of Armenia, School of Public Health, Yerevan, Armenia.
Ruzanna PapyanYerevan State Medical University, Yerevan, Armenia. Email: gevorgtamamyan@gmail.com
Samvel DanielyanArmenian Pediatric Hematology and Oncology Group, Yerevan, Armenia.
Lilit SargsyanYerevan State Medical University, Yerevan, Armenia. Email: gevorgtamamyan@gmail.com
Varduhi GrigoryanMinistry of Health of the Republic of Armenia, Yerevan, Armenia.
Hakob TopchyanScientific Center of Drug and Medical Technology Expertise, Yerevan, Armenia.
Arpina AzaryanScientific Center of Drug and Medical Technology Expertise, Yerevan, Armenia.
Armen TananyanYerevan State Medical University, Yerevan, Armenia. Email: gevorgtamamyan@gmail.com
Armen MuradyanYerevan State Medical University, Yerevan, Armenia. Email: gevorgtamamyan@gmail.com
Gevorg TamamyanYerevan State Medical University, Yerevan, Armenia. Email: gevorgtamamyan@gmail.com
Yerevan State Medical University · AMInstitute of Fine Organic Chemistry of Scientific - Technological Center of Organic and Pharmaceutical Chemistry · AMAmerican University of Armenia · AMScientific Center of Zoology and Hydroecology · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: One of the main contributors in low survival rate in LMIC is the lack of availability of cancer medications for curative, supportive and palliative care. In many developing countries access to cytotoxic medicine is a major challenge. The information about the availability of essential medicines for pediatric cancer in the country is not known. The main objective of this study was to determine whether the medications used during the treatment of pediatric cancer are available in Armenia. Methods: In summer 2016 we conducted a survey in the 3 main pharmacies in Yerevan, which import pediatric cancer medications to Armenia to evaluate whether medications used during cancer treatment are officially registered and available in the country. In addition, the information on official registration was cross-checked with the Ministry of Health of the Republic of Armenia (MOH). Simultaneously, detailed information about the drugs, on type of produced drug company, doses and price intervals was confined from the price lists of the national drug importer companies. Results: The survey included 64 agents in three classes of medication: anti-neoplastics, anti-microbials, and drugs used in supportive care. All of these medications were included in the recent version of the WHO model list of essential medicines. From 30 anti-neoplastic medications on the essential medicines list 22 (73%) were officially registered in Armenia; from 19 anti-microbial drugs all were registered except caspofungin and from 15 supportive care agents 13 (87%) were registered. From registered anti-neoplastic drugs 18% and from antimicrobial drugs 33% were not available in the drug stores. Conclusion: This study showed that not all the drugs from the SIOP PODC Essential Medication list for pediatric oncology are officially registered and available in Armenia, and effective drug regulation focusing on the childhood cancer care medicine is needed for improving the situation in the country.

Indexed as

Health Services AccessibilityAntineoplastic AgentsArmeniaChildDeveloping CountriesDrugs, EssentialFollow-Up StudiesHumansNeoplasmsPharmaciesPrognosisSurveys and QuestionnairesAntineoplastic AgentsDrugs, EssentialArmeniacancerOncology

Identifiers

PMID31030465
PMCPMC6948909
OpenAlexW2938543414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.