Trial reportLasers in medical science2020
The effect of a single irradiation of low-level laser on nipple pain in breastfeeding women: a randomized controlled trial.
Trial report in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07370051 (Effect of Topical Oxygen and LED Light Therapy on Nipple Crack), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Topical Oxygen and LED Light Therapy on Nipple Crack: A Randomized Controlled Trial
Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Photobiomodulation as a promising approach in the management of nipple lesions during breastfeeding: a systematic review and meta-analysis of randomized clinical trials.Lasers in medical science · 2025Pooled it
- Low-level laser therapy for nipple trauma and pain during breastfeeding: systematic review and meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Pooled it
- Interventions for breastfeeding-related nipple pain or injury: a meta-analysis.Frontiers in global women's health · 2025Pooled it
- Initial nipple damages in breastfeeding women: analysis of photographic images and clinical associations.Revista brasileira de enfermagem · 2023Trial
- Adjuvant Effect of Photobiomodulation in the Pain Relief and Healing of Ulcerative Lesions from Mammary Tuberculosis.The American journal of tropical medicine and hygiene · 2025Article
- Could Photobiomodulation help lactating women and their newborns?Lasers in medical science · 2024Article
- Article
- Opinion of speech-language pathologist on the use of photobiomodulation in the vocal clinic.CoDAS · 2023Observational
- Re-thinking lactation-related nipple pain and damage.Women's health (London, England)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Photobiomodulation with low-level laser therapy (PBM-LLLT) has been introduced as a new tool to relieve nipple pain and repair nipple damage in breastfeeding women; however, evidence is needed to assess its effectiveness. The aim was to evaluate the effect of a single application of PBM-LLLT for breastfeeding women with nipple pain and damage; side effects were also collected. We conducted a randomized double-blinded controlled trial with women with nipple damage who were exclusively breastfeeding and rooming-in at Amparo Maternal maternity service, São Paulo, Brazil (May 2016 to May 2017). Women were randomly assigned into laser (n = 40) or control group (n = 40). Intervention was a single irradiation (660 nm, 100 mW, 2 J, 66.66 J/cm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.