Evidence map›Paper›PMID 31030258›Full record

Observational studyEuropean journal of pediatrics2019

Developmental and behavioral problems in preschool-aged primary ciliary dyskinesia patients.

P Zengin Akkus, M Gharibzadeh Hizal, E Ilter Bahadur, E N Ozmert, S Eryilmaz Polat, G Ozdemir, S Karahan, E Yalcin, D Dogru Ersoz, N Kiper and 1 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Is Quarantine for COVID-19 Pandemic Associated with Psychological Burden in Primary Ciliary Dyskinesia?International journal of environmental research and public health · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

P Zengin AkkusFaculty of Medicine, Department of Pediatrics, Division of Developmental Pediatrics, Hacettepe University, Ankara, Turkey. pinarzenginakkus@gmail.com.ORCID http://orcid.org/0000-0003-1704-0327
M Gharibzadeh HizalFaculty of Medicine, Department of Pediatrics, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.
E Ilter BahadurFaculty of Medicine, Department of Pediatrics, Division of Developmental Pediatrics, Hacettepe University, Ankara, Turkey.
E N OzmertFaculty of Medicine, Department of Pediatrics, Division of Developmental Pediatrics, Hacettepe University, Ankara, Turkey.
S Eryilmaz PolatFaculty of Medicine, Department of Pediatrics, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.
G OzdemirFaculty of Medicine, Department of Pediatrics, Division of Developmental Pediatrics, Hacettepe University, Ankara, Turkey.
S KarahanFaculty of Medicine, Department of Biostatistics, Hacettepe University, Ankara, Turkey.
E YalcinFaculty of Medicine, Department of Pediatrics, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.
D Dogru ErsozFaculty of Medicine, Department of Pediatrics, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.
N KiperFaculty of Medicine, Department of Pediatrics, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.
U OzcelikFaculty of Medicine, Department of Pediatrics, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary ciliary dyskinesia (PCD) causes a broad spectrum of disease. This study aims to explore the developmental, behavioral, and social-emotional aspects of preschool-aged children with PCD. Fourteen PCD, 17 cystic fibrosis (CF) patients and 15 healthy subjects were enrolled. Developmental features of the participants were evaluated with Ages and Stages Questionnaire. Parents of participants filled out the Child Behavior Checklist (CBCL). The number of children screened positive for developmental delay was statistically higher in the PCD group. Higher numbers of children with PCD were screened positive for developmental delay in communication and problem-solving domains. Delay in fine motor skill domain was more common in children with PCD and CF compared to healthy subjects. There was no difference among the three groups in terms of gross motor and personal-social development. None of the children in all three groups was shown to have social-emotional problems. In CBCL, patients with CF had higher internalizing problem scores. Externalizing and total problem scores did not differ between the three groups. However, among PCD patients, children with developmental delay on more than one domain had higher externalizing and total problem scores.Conclusion: The current study revealed that positive screening for developmental delay is more common in preschool-aged PCD patients compared to patients with CF and healthy children. What is Known: • Intelligence scores of school-aged PCD patients are similar to healthy subjects despite their higher internalizing problem scores on Child Behavior Checklist (CBCL). • School-aged PCD patients exhibit higher hyperactivity and inattention findings. What is New: • Positive screening for developmental delay in communication, problem-solving and fine motor skills is more common in preschool-aged PCD patients. • Preschool-aged PCD patients screened positive for developmental delay in more than one domain have higher externalizing and total problem scores on CBCL.

Indexed as

Behavior Rating ScaleCase-Control StudiesChild Behavior DisordersChild, PreschoolCiliary Motility DisordersCohort StudiesDevelopmental DisabilitiesFemaleHumansMaleRisk FactorsBehavioral problemsDevelopmental delayPrimary ciliary dyskinesiaSocial-emotional problems

Identifiers

PMID31030258
OpenAlexW2941536019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.