Evidence map›Paper›PMID 31030229›Full record

Trial reportWorld journal of urology2020

Clinical efficacy and safety of flexible ureteroscopic lithotripsy using 365 μm holmium laser for nephrolithiasis: a prospective, randomized, controlled trial.

Pei Lu, Keliang Chen, Zijie Wang, Rijin Song, Jiexiu Zhang, Bianjiang Liu, Guohua Zeng, Zengjun Wang, Wei Zhang, Min Gu

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Pei LuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Keliang ChenDepartment of Urology, Ningbo First Hospital, Ningbo, 315000, China.
Zijie WangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Rijin SongDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Jiexiu ZhangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Bianjiang LiuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Guohua ZengDepartment of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510230, China.
Zengjun WangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Wei ZhangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. njmuwzj@qq.com.
Min GuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. lancetgu@aliyun.com.ORCID http://orcid.org/0000-0003-1054-9200
Jiangsu Province Hospital · CNFirst Affiliated Hospital of Guangzhou Medical University · CNNingbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the clinical efficacy and safety between the FURL with 365 μm and 200 μm holmium laser for treating nephrolithiasis. MATERIALS AND

methodsA prospective randomized controlled trial was performed including analysis of data from 200 patients with nephrolithiasis. A total of 180 patients were randomized into two groups according to 1:1 ratio. In the 365 μm holmium laser group, kidney stones were disintegrated into less than 2 mm fragments with a 365 µm holmium laser fiber with the settings of 30-45 W under direct visualization; in the control group, the conventional 200 μm holmium laser was used. Descriptive statistics and logistic regression analyses tested the association among operation time, stone-free rate (SFR) and incidence of complications.

resultsOperation time in the FURL with 365 μm laser was significantly shortened and no significance was observed in the complication rate. Stone size and location were identified as two major confounding factors for the operation time and SFR. Moreover, the FURL using 365 μm laser showed less operation time for renal stones with the diameter between 1 and 2 cm, stones located in lower calyx and multiple calculi; stones larger than 2 cm and/or located in lower pole inclined to present better SFR using the FURL with 365 μm laser.

conclusionsThe FURL combined with 365 μm holmium laser is safer and highly efficacious for the management of nephrolithiasis when compared to conventional FURL procedures, especially for those located in lower pole and larger than 2 cm.

Indexed as

AdolescentAdultFemaleHumansKidney CalculiLasers, Solid-StateLithotripsy, LaserMaleMiddle AgedOperative TimeProspective StudiesTreatment OutcomeUreteroscopyYoung Adult365 μm Holmium laserEfficacyFlexible ureteroscopy lithotripsyNephrolithiasisSafety

Identifiers

PMID31030229
OpenAlexW2941487623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.