ArticleJournal of natural medicines2019
Three new alkaloids from the roots of Sophora tonkinensis.
Article in Journal of natural medicines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Genes involved in the regulation of alkaloid and flavonoid biosynthesis in different tissues of Sophora tonkinensis via transcriptomics and metabolomics.BMC plant biology · 2025Article
- Identification, Formation, and Occurrence of Perlolyrine: A β-Carboline Alkaloid with a Furan Moiety in Foods.Journal of agricultural and food chemistry · 2023Article
- Flavonoids from the roots and rhizomes of Sophoratonkinensis and their in vitro anti-SARS-CoV-2 activity.Chinese journal of natural medicines · 2023Article
- Biological Activities and Secondary Metabolites fromMolecules (Basel, Switzerland) · 2022Review
- Chemical Constituents from the Roots and Rhizomes ofACS omega · 2022Article
- Five matrine-type alkaloids from Sophora tonkinensis.Journal of natural medicines · 2021Article
- Preparative Purification of Total Flavonoids fromMolecules (Basel, Switzerland) · 2019Article
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Authors and funding
7 authors.
Funding
Abstract
A new β-carboline alkaloid (1) and two new matrine-type alkaloids (2 and 3), together with two known alkaloids (4 and 5), were isolated from the roots of Sophora tonkinensis. The new structures were elucidated via extensive analyses of the spectroscopic data (IR, UV, HRESIMS, NMR) and X-ray crystallography. The absolute configuration of 1 was established by electronic circular dichroism data. Herein, is the first report of β-carboline alkaloid in the plant of genus Sophora. In addition, the cytotoxic activities against HepG2 cells of compounds 1-5 were evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Among them, compounds 1, 4 and 5 showed a weak cytotoxic activity with IC
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