Evidence map›Paper›PMID 31028614›Full record

ArticleAdvances in therapy2019

Two-Year Outcomes After Aquablation Compared to TURP: Efficacy and Ejaculatory Improvements Sustained.

Peter Gilling, Neil Barber, Mohamed Bidair, Paul Anderson, Mark Sutton, Tev Aho, Eugene Kramolowsky, Andrew Thomas, Barrett Cowan, Ronald P Kaufman and 9 more

2 registry-linked trialsOpen access · hybridAbstract readComparative Study
In one paragraph

Article in Advances in therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02505919 nacompletednot on this map

A Prospective Multicenter Randomized Blinded Study Comparing Aquablation of the Prostate With the AQUABEAM System and TURP for the Treatment of LUTS

TypeinterventionalSponsorPROCEPT BioRoboticsRan2015 to 2021Enrolled184ConditionsBenign Prostatic Hyperplasia (BPH)ArmsAQUABEAM System, Transurethral Resection of the Prostate (TURP)
NCT04658056 unknown statusnot on this mapstarted 2021, after this paper: background citation

The UK POST WATERStudy: UK Post-market Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue

TypeobservationalSponsorPROCEPT BioRoboticsRan2021 to 2022Enrolled46ConditionsBenign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  18. Reasons to overthrow TURP: bring on Aquablation.World journal of urology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 4 countries.

Peter GillingTauranga Urology Research, Tauranga, New Zealand. peter@urobop.co.nz.
Neil BarberFrimley Park Hospital, Frimley Health Foundation Trust, Surrey, UK.
Mohamed BidairSan Diego Clinical Trials, San Diego, CA, USA.
Paul AndersonRoyal Melbourne Hospital, Melbourne, Australia.
Mark SuttonHouston Metro Urology, Houston, TX, USA.
Tev AhoAddenbrooke's Hospital, Cambridge University Hospitals, Cambridge, UK.
Eugene KramolowskyVirginia Urology, Richmond, VA, USA.
Andrew ThomasPrincess of Wales Hospital, Bridgend, Wales, UK.
Barrett CowanUrology Associates, P.C., Englewood, CO, USA.
Ronald P KaufmanAlbany Medical College, Albany, NY, USA.
Andrew TrainerAdult Pediatric Urology & Urogynecology, P.C., Omaha, NE, USA.
Andrew ArtherAdult Pediatric Urology & Urogynecology, P.C., Omaha, NE, USA.
Gopal BadlaniWake Forest School of Medicine, Winston-Salem, NC, USA.
Mark PlanteUniversity of Vermont Medical Center, Burlington, VT, USA.
Mihir DesaiInstitute of Urology, University of Southern California, Los Angeles, CA, USA.
Leo DoumanianInstitute of Urology, University of Southern California, Los Angeles, CA, USA.
Alexis E TeWeill Cornell Medical College, New York, NY, USA.
Mark DeGuentherUrology Centers of Alabama, Birmingham, AL, USA.
Claus RoehrbornDepartment of Urology, UT Southwestern Medical Center, University of Texas Southwestern, Dallas, TX, USA.
Adult and Pediatric Dermatology · USUniversity of Southern California · USAlbany Medical Center Hospital · USCornell University · USHealth Foundation · GBLos Angeles Clinical Trials · USMetro Urology · USPrincess of Wales Hospital · GBTauranga Hospital · NZThe Royal Melbourne Hospital · AUThe University of Texas Southwestern Medical Center · USUniversity of Cambridge · GBUniversity of Vermont Medical Center · USUrology Associates · USUrology of Virginia · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo compare 2-year safety and efficacy outcomes after Aquablation or transurethral resection of the prostate (TURP) for the treatment of lower urinary tract symptoms related to benign prostate hyperplasia (BPH).

methodsOne hundred eighty-one patients with BPH were assigned at random (2:1 ratio) to either Aquablation or TURP. Patients and follow-up assessors were blinded to treatment. Assessments included the International Prostate Symptom Score (IPSS), Male Sexual Health Questionnaire (MSHQ), International Index of Erectile Function and uroflow. The focus of analysis was 2-year outcomes.

resultsAt 2 years, IPSS scores improved by 14.7 points in the Aquablation group and 14.9 points in TURP (p = .8304, 95% CI for difference - 2.1 to 2.6 points). Two-year improvements in maximum flow rate (Q

conclusionTwo-year efficacy outcomes after TURP and Aquablation were similar, and the rate of surgical retreatment was low and similar to TURP.

trial registrationClinicalTrials.gov no. NCT02505919.

fundingPROCEPT BioRobotics.

Indexed as

WaterAblation TechniquesAgedHumansLower Urinary Tract SymptomsMaleMiddle AgedProstatic HyperplasiaTransurethral Resection of ProstateWaterAquablationBPHRobotic surgeryTURPUrology

Identifiers

PMID31028614
PMCPMC6824383
OpenAlexW2941597585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.