Evidence map›Paper›PMID 31028518›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2019

Posterior box isolation as an adjunctive ablation strategy during repeat ablation with the second-generation cryoballoon for recurrence of persistent atrial fibrillation: 1-year follow-up.

Saverio Iacopino, Gaetano Paparella, Lucio Capulzini, Erwin Ströker, Stefan Beckers, Thiago Guimarães Osório, Varnavas Varnavas, Juan Sieira, Juan Pablo Abugattas, Riccardo Maj and 6 more

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Outcomes after redo ablation for the recurrence of atrial fibrillation: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  3. Prospective evaluation of low voltage-guided repeat ablation of atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  4. Innovations in atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Review
  5. Article
  6. Article
  7. Persistent atrial fibrillation: should we always ice the back of the left atrium?Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Saverio IacopinoElectrophysiology Unit, Villa Maria Cecilia Hospital, Gruppo Villa Maria, Cotignola, Italy.
Gaetano PaparellaHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Lucio CapulziniHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Erwin StrökerHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Stefan BeckersHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Thiago Guimarães OsórioHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Varnavas VarnavasHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Juan SieiraHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Juan Pablo AbugattasHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Riccardo MajHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Francesca SalghettiHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Vincent UmbrainHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Muryo TerasawaHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Pedro BrugadaHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Carlo de AsmundisHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium.
Gian Battista ChierchiaHeart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Vrije Universiteit, Brussels, Belgium. gbchier@yahoo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe creation of a posterior box isolation of the left atrium (LAPWI) in addition to pulmonary vein isolation (PVI) with the second-generation cryoballoon (CB-A) seems to offer promising clinical outcome in patients affected by persistent atrial fibrillation (PersAF).

aimThis work aims to study the clinical outcome of an ablation strategy based on the creation of a LAPWI during repeat procedures for recurrent AF after an index CB-A procedure for PersAF. METHODS AND

resultsA total of 33 patients having undergone a repeat procedure consisting in redo PVI plus LAPWI for recurrent PersAF with the CB-A after an index PVI ablation were retrospective included in our study. Electrical reconnection could be documented in 18 veins (13%). The LAPW was successfully isolated solely by CB-A ablation in 30 out of 33 (91%) patients; in the remaining 3 patients, isolation of the LAPW was completed by focal tip-irrigated RF ablation. The mean number of CB-A applications required for the superior portion of the LAPW and the inferior portion of the LAPW creation were 5.4 ± 0.9 and 4 ± 0.6, respectively. After a mean follow-up of 11.8 ± 3 months, 28 patients (85%) did not experience recurrence of any atrial arrhythmias during follow-up, without the need of further ablation or class I or III AADs.

conclusionLeft posterior wall isolation with the CB-A is feasible and safe during repeat ablation procedures for recurrent PersAF. In our study, the 12-month freedom from any arrhythmia was 85% following this ablation strategy.

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryFemaleFollow-Up StudiesHeart AtriaHumansMaleMiddle AgedPulmonary VeinsRecurrenceRetrospective StudiesAblationCryoballoonPersistent atrial fibrillationPulmonary vein isolationRepeat procedures

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.