Evidence map›Paper›PMID 31028517›Full record

ArticleCell and tissue banking2019

Gender differential in inclination to donate brain for research among Nigerians: the IBADAN Brain Bank Project.

Rufus Akinyemi, Akin Ojagbemi, Joshua Akinyemi, Ayodeji Salami, Funmi Olopade, Temitope Farombi, Michael Nweke, Ezinne Uvere, Mayowa Aridegbe, James Balogun and 6 more

Abstract read
In one paragraph

Article in Cell and tissue banking, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Strengthening Brain Research in Africa.Journal of Alzheimer's disease reports · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rufus AkinyemiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria. rufusakinyemi@yahoo.com.ORCID http://orcid.org/0000-0001-5286-428X
Akin OjagbemiDepartment of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Joshua AkinyemiDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Ayodeji SalamiDepartment of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Funmi OlopadeDepartment of Anatomy, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Temitope FarombiChief Tony Anenih Geriatric Centre, University College Hospital, Ibadan, Nigeria.
Michael NwekeDepartment of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Ezinne UvereDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Mayowa AridegbeInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
James BalogunDepartment of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Godwin OgboleDepartment of Radiology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Ayodele JegedeDepartment of Sociology, Faculty of the Social Sciences, University of Ibadan, Ibadan, Nigeria.
Rajesh KalariaInstitute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.
Adesola OgunniyiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Mayowa OwolabiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Oyedunni ArulogunDepartment of Health Promotion and Education, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Funding

Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
African Neurobiobank for Precision Stroke Medicine - (ELSI) ProjectU01HG010273 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI AKINYEMI, RUFUS OLUSOLA, ARULOGUN, OYEDUNNI SOLA · 2018 to 2022
$512k
Medical Research Council G1100540National Institutes of Health (US) R01NS107900NHGRI NIH HHS U01 HG010273NHGRI NIH HHS U54 HG007479NIH HHS U01HG010273NIH HHS U54HG007479NINDS NIH HHS R01 NS107900
6 · The paper itself

Abstract

backgroundLaboratory-based studies of neurological disease patterns and mechanisms are sparse in sub-Saharan Africa. However, availability of human brain tissue resource depends on willingness towards brain donation. This study evaluated the level of willingness among outpatient clinic attendees in a Nigerian teaching hospital.

methodsUnder the auspices of the IBADAN Brain Bank Project, a 43-item semi-structured interviewer-administered questionnaire was designed to evaluate knowledge, attitude, and beliefs of individuals attending Neurology, Psychiatry and Geriatrics Outpatient clinics regarding willingness to donate brain for research. Association between participants characteristics and willingness towards brain donation was investigated using logistic regression models. Analysis was conducted using Stata SE version 12.0.

resultsA total of 412 participants were interviewed. Their mean age was 46.3 (16.1) years. 229 (55.6%) were females and 92.5% had at least 6 years of formal education. Overall, 109 (26.7%) were willing to donate brains for research. In analyses adjusting for educational status, religion, ethnicity, marital status and family setting, male sex showed independent association with willingness towards brain donation OR (95% CI) 1.7 (1.08-2.69), p = 0.023. Participants suggested public engagement and education through mass media (including social media) and involvement of religious and community leaders as important interventions to improve awareness and willingness towards brain donation.

conclusionThe survey revealed low willingness among outpatient clinic attendees to donate brain for research, although men were more inclined to donate. It is imperative to institute public engagement and educational interventions in order to improve consent for brain donation for research.

Indexed as

Health Knowledge, Attitudes, PracticeAdultBiomedical ResearchBrainFemaleHumansMaleMiddle AgedNigeriaSex DistributionSex FactorsSurveys and QuestionnairesTissue and Organ ProcurementTissue BanksAfricaBrain bankingBrain donationLMICNigeriaWillingness

Identifiers

PMID31028517
PMCPMC6556418

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.