Evidence map›Paper›PMID 31028504›Full record

ReviewNeurochemical research2020

Biomaterials and Magnetic Stem Cell Delivery in the Treatment of Spinal Cord Injury.

Šárka Kubinová

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Šárka KubinováInstitute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220, Prague, Czech Republic. sarka.kubinova@iem.cas.cz.
Czech Academy of Sciences, Institute of Experimental Medicine · CZ

Funding

Grantová Agentura České Republiky 17-03765SGrantová Agentura České Republiky 19-10365SMinisterstvo Školství, Mládeže a Tělovýchovy CZ.02.1.01/0.0./0.0/15_003/0000419
6 · The paper itself

Abstract

Spinal cord injury (SCI) is a serious trauma, which often results in a permanent loss of motor and sensory functions, pain and spasticity. Despite extensive research, there is currently no available therapy that would restore the lost functions after SCI in human patients. Advanced treatments use regenerative medicine or its combination with various interdisciplinary approaches such as tissue engineering or biophysical methods. This review summarizes and critically discusses the research from specific interdisciplinary fields in SCI treatment such as the development of biomaterials as scaffolds for tissue repair, and using a magnetic field for targeted cell delivery. We compare the treatment effects of synthetic non-degradable methacrylate-based hydrogels and biodegradable biological scaffolds based on extracellular matrix. The systems using magnetic fields for magnetically guided delivery of stem cells loaded with magnetic nanoparticles into the lesion site are then suggested and discussed.

Indexed as

AnimalsBiocompatible MaterialsHumansHydrogelsMagnetic Field TherapyNerve RegenerationSpinal Cord InjuriesStem Cell TransplantationBiocompatible MaterialsHydrogelsBiomaterialsCell deliveryHydrogelMagnetic fieldSpinal cord injury

Identifiers

PMID31028504
OpenAlexW2941686342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.