Evidence map›Paper›PMID 31028487›Full record

ArticleMedical oncology (Northwood, London, England)2019

Postmastectomy radiation therapy using VMAT technique for breast cancer patients with expander reconstruction.

Fiorenza De Rose, Antonella Fogliata, Davide Franceschini, Salvatore Cozzi, Cristina Iftode, Antonella Stravato, Stefano Tomatis, Giovanna Masci, Rosalba Torrisi, Alberto Testori and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Recent advances in radiotherapy of breast cancer.Radiation oncology (London, England) · 2020
    Review
  12. Article
  13. Modeling AeroForm tissue expander for postmastectomy radiation therapy.Journal of applied clinical medical physics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Fiorenza De RoseRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Antonella FogliataRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy. antonella.fogliata@humanitas.it.ORCID http://orcid.org/0000-0002-2282-9894
Davide FranceschiniRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Salvatore CozziRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Cristina IftodeRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Antonella StravatoRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Stefano TomatisRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Giovanna MasciMedical Oncology Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Rosalba TorrisiMedical Oncology Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Alberto TestoriBreast Surgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Corrado TinterriBreast Surgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Andrea V E LisaPlastic Surgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Luca MaionePlastic Surgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Valeriano VinciPlastic Surgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Marco KlingerPlastic Surgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Armando SantoroMedical Oncology Department, Humanitas Research Hospital, Milan, Rozzano, Italy.
Marta ScorsettiRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan, Rozzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postmastectomy radiotherapy (PMRT) following immediate breast reconstruction is increasingly adopted in the management of breast cancer patients. We retrospectively evaluate the complication rates of PMRT using VMAT technique to immediate tissue expander-based reconstructions and the possible impact of tissue expander volume on radiotherapy planning. We reviewed the data of patients who underwent immediate expander breast reconstruction and received PMRT with VMAT (50 Gy in 25 fractions) on the reconstructed breast and axillary levels III-IV. Neoadjuvant or adjuvant systemic therapy was administered in most of the patients. Autologous fat grafting was routinely performed at the time of second-stage reconstruction. Between 2015 and 2017, PMRT was delivered to 46 consecutive patients (median age 50 years) with expander reconstruction. Median follow-up was 27 months (range 10-41). Two patients (4.3%) had a reconstruction failure, as expander rupture and infection, following the first- and the second-stage reconstruction, respectively. In most cases expanders were completely inflated before PMRT (65.2%). Median expander volume before PMRT was 425 cm

Indexed as

Breast ImplantsAdultAgedBreast NeoplasmsCombined Modality TherapyDose Fractionation, RadiationFemaleHumansMammaplastyMastectomyMiddle AgedPostoperative ComplicationsRadiotherapy, AdjuvantRadiotherapy Planning, Computer-AssistedRetrospective StudiesTissue Expansion DevicesAutologous fat graftingImmediate breast reconstructionPostmastectomy radiotherapyTissue expanderVMAT

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.