Evidence map›Paper›PMID 31028483›Full record

ReviewCurrent treatment options in cardiovascular medicine2019

Psychosocial Stress and Cardiovascular Disease.

Tawseef Dar, Azar Radfar, Shady Abohashem, Roger K Pitman, Ahmed Tawakol, Michael T Osborne

Open access · greenAbstract readReview
In one paragraph

Review in Current treatment options in cardiovascular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 2 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 2 syntheses or guidelines pooled it, 241 citations in OpenAlex.

  1. Pooled it
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  15. Novel neurotherapeutic targets for substance use disorders: Neuroplasticity, neuroinflammation, gasotransmitters and non-canonical organ systems.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
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  20. The Science of Tai Chi andJournal of integrative and complementary medicine · 2025
    Review

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tawseef DarCardiac MR-PET-CT Program, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Azar RadfarCardiac MR-PET-CT Program, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Shady AbohashemCardiac MR-PET-CT Program, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Roger K PitmanDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Ahmed TawakolCardiac MR-PET-CT Program, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Michael T OsborneCardiac MR-PET-CT Program, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA. mosborne@mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · US

Funding

Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Filip K Swirski · 2017 to 2026
$24.3M
Institutional Career Development CoreKL2TR002542 · NCATS · HARVARD MEDICAL SCHOOL · PI BREDELLA, MIRIAM ANTOINETTE, RUTKOVE, SEWARD B. · 2018 to 2022
$8.7M
American Heart Association-American Stroke Association 18CDA34110366NCATS NIH HHS KL2 TR002542NHLBI NIH HHS P01 HL131478
6 · The paper itself

Abstract

purpose of reviewThis manuscript reviews the epidemiological data linking psychosocial stress to cardiovascular disease (CVD), describes recent advances in understanding the biological pathway between them, discusses potential therapies against stress-related CVD, and identifies future research directions. RECENT

findingsMetabolic activity of the amygdala (a neural center that is critically involved in the response to stress) can be measured on

Indexed as

Amygdalar activityCardiovascular diseasePET imagingPsychosocial stress

Identifiers

PMID31028483
PMCPMC6568256
OpenAlexW2940673845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.