Evidence map›Paper›PMID 31028448›Full record

ArticleEuropean radiology2019

Autosomal dominant polycystic kidney disease: new role for ultrasound.

Hakan İmamoğlu, Gökmen Zararsız, Serap Doğan, İsmail Koçyiğit, Eray Eroğlu, Ahmet Öztürk, Nuri Erdoğan

Abstract readEvaluation Study
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In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hakan İmamoğluDepartment of Radiology, Erciyes University Medical Faculty, 38039, Kayseri, Turkey. drhimamoglu@hotmail.com.ORCID http://orcid.org/0000-0002-2933-662X
Gökmen ZararsızDepartment of Biostatistics, Erciyes University Medical Faculty, Kayseri, Turkey.
Serap DoğanDepartment of Radiology, Erciyes University Medical Faculty, 38039, Kayseri, Turkey.
İsmail KoçyiğitDepartment of Nephrology, Erciyes University Medical Faculty, Kayseri, Turkey.
Eray EroğluDepartment of Nephrology, Erciyes University Medical Faculty, Kayseri, Turkey.
Ahmet ÖztürkDepartment of Biostatistics, Erciyes University Medical Faculty, Kayseri, Turkey.
Nuri ErdoğanDepartment of Radiology, Erciyes University Medical Faculty, 38039, Kayseri, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the accuracy of US in calculating renal volumes and renal resistive index (RRI) that was obtained using a new method in patients with autosomal dominant polycystic kidney disease (ADPKD).

methodsIn this prospective study, US and MRI were performed in 57 patients with ADPKD (31 female and 26 male; age range, 19-79 years) between August 2017 and May 2018. The volumes determined using US and MRI were compared. The ellipsoid formula was re-evaluated using different multipliers. RRI was obtained 1.5-2 cm distal to the outlet of main renal arteries. The relationship between mean RRI, renal function tests, and kidney volumes and difference between mean RRI of ADPKD patients with and without renal failure were investigated using a two-sided independent samples t test and Pearson correlation test. Interobserver agreements for volume assessments and RRI measurements were determined.

resultsBy changing the ellipsoid formula, a very good agreement was found (ICC 0.970 for the right kidney and ICC 0.973 for the left kidney). The mean RRI in the right renal artery was 0.61 ± 0.07 and in the left renal artery 0.63 ± 0.06. The mean RRI of ADPKD patients with renal failure was significantly higher than that of patients without renal failure (p = 0.005). There was a significant correlation between mean RRI and renal function tests.

conclusionThe accuracy of the US in calculating renal volumes increases by adapting the ellipsoid formula. RRI may be used for the management of ADPKD independently of volumes. KEY POINTS: •The accuracy of ultrasonography for renal volume measurement increases by changing the classical ellipsoid formula. •Renal resistive index measured by color Doppler ultrasonography is helpful for the management of autosomal dominant polycystic kidney disease. •The role of Doppler US in autosomal dominant polycystic kidney disease should increase as a result of our findings.

Indexed as

AdultAgedFeasibility StudiesFemaleHumansKidneyMagnetic Resonance ImagingMaleMiddle AgedPolycystic Kidney, Autosomal DominantProspective StudiesRenal ArteryRenal InsufficiencyUltrasonography, Doppler, ColorYoung AdultKidneyPolycystic kidney, autosomal dominantRenal arteryRenal insufficiencyUltrasonography, Doppler

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.