Evidence map›Paper›PMID 31028445›Full record

Observational studyEuropean radiology2019

Tumour necrosis as assessed with

Xaver U Kahle, Menno Hovingh, Walter Noordzij, Annika Seitz, Arjan Diepstra, Lydia Visser, Anke van den Berg, Tom van Meerten, Gerwin Huls, Ronald Boellaard and 2 more

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. An incidental finding behind adrenal incidentaloma.Endocrinology, diabetes & metabolism case reports · 2022
    Article
  4. Article
  5. Multiple metabolic parameters and visual assessment ofAbdominal radiology (New York) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xaver U KahleDepartment of Hematology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. x.kahle@umcg.nl.ORCID http://orcid.org/0000-0001-8248-7008
Menno HovinghDepartment of Hematology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Walter NoordzijDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Annika SeitzDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Arjan DiepstraDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Lydia VisserDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Anke van den BergDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Tom van MeertenDepartment of Hematology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Gerwin HulsDepartment of Hematology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Ronald BoellaardDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Thomas C KweeDepartment of Radiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Marcel NijlandDepartment of Hematology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMYC gene rearrangements in diffuse large B cell lymphomas (DLBCLs) result in high proliferation rates and are associated with a poor prognosis. Strong proliferation is associated with high metabolic demand and tumour necrosis. The aim of this study was to investigate differences in the presence of necrosis and semiquantitative

methodsFluorescence in situ hybridisation analysis for MYC rearrangements, visual assesment, semiquantitative analysis of

resultsOf 61 tumours, 21 (34%) had a MYC rearrangement (MYC

conclusionsMYC rearrangements in DLBCL have no influence on the visual parameter necrosis KEY POINTS: • Retrospective analysis indicates that MYC rearrangement is not associated with necrosis on

Indexed as

Fluorodeoxyglucose F18RadiopharmaceuticalsAdultAgedFemaleGene Rearrangement, B-LymphocyteGenes, mycGlycolysisHumansLymphoma, Large B-Cell, DiffuseMaleMiddle AgedMultivariate AnalysisPositron-Emission TomographyPrognosisRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsDiffuse, large B cell, lymphomaFluorodeoxyglucose F18MYC oncogeneNecrosisPositron emission tomography

Identifiers

PMID31028445
PMCPMC6795618
OpenAlexW2940880674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.