Evidence map›Paper›PMID 31028270›Full record

ReviewNPJ primary care respiratory medicine2019

The health and social implications of household air pollution and respiratory diseases.

Suzanne M Simkovich, Dina Goodman, Christian Roa, Mary E Crocker, Gonzalo E Gianella, Bruce J Kirenga, Robert A Wise, William Checkley

Open access · goldAbstract readReview
In one paragraph

Review in NPJ primary care respiratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. Pulmonary Health Effects of Indoor Volatile Organic Compounds-A Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  3. Trial
  4. Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Suzanne M SimkovichDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Dina GoodmanDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Christian RoaCenter for Global Non-Communicable Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Mary E CrockerCenter for Global Non-Communicable Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-0587-1249
Gonzalo E GianellaFacultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru.
Bruce J KirengaMakerere Lung Institute, Makerere University, Kampala, Uganda.
Robert A WiseDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. wcheckl1@jhmi.edu.
Johns Hopkins University · USMulago Hospital · UGUniversidad Peruana Cayetano Heredia · PE

Funding

Household Air Pollution and Health: A Multi-Country LPG Intervention TrialUM1HL134590 · NHLBI · EMORY UNIVERSITY · PI CHECKLEY, WILLIAM, CLASEN, THOMAS F · 2016 to 2021
$31.1M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
FIC NIH HHS R25 TW009340NHLBI NIH HHS UM1 HL134590
6 · The paper itself

Abstract

Approximately three billion individuals are exposed to household air pollution (HAP) from the burning of biomass fuels worldwide. Household air pollution is responsible for 2.9 million annual deaths and causes significant health, economic and social consequences, particularly in low- and middle-income countries. Although there is biological plausibility to draw an association between HAP exposure and respiratory diseases, existing evidence is either lacking or conflicting. We abstracted systematic reviews and meta-analyses for summaries available for common respiratory diseases in any age group and performed a literature search to complement these reviews with newly published studies. Based on the literature summarized in this review, HAP exposure has been associated with acute respiratory infections, tuberculosis, asthma, chronic obstructive pulmonary disease, pneumoconiosis, head and neck cancers, and lung cancer. No study, however, has established a causal link between HAP exposure and respiratory disease. Furthermore, few studies have controlled for tobacco smoke exposure and outdoor air pollution. More studies with consistent diagnostic criteria and exposure monitoring are needed to accurately document the association between household air pollution exposure and respiratory disease. Better environmental exposure monitoring is critical to better separate the contributions of household air pollution from that of other exposures, including ambient air pollution and tobacco smoking. Clinicians should be aware that patients with current or past HAP exposure are at increased risk for respiratory diseases or malignancies and may want to consider earlier screening in this population.

Indexed as

Air Pollution, IndoorFamily CharacteristicsHumansInhalation ExposureRespiratory Tract DiseasesRisk FactorsTobacco Smoke PollutionTobacco Smoke Pollution

Identifiers

PMID31028270
PMCPMC6486605
OpenAlexW2940737659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.