Evidence map›Paper›PMID 31028253›Full record

ArticleNature communications2019

Human-sized magnetic particle imaging for brain applications.

M Graeser, F Thieben, P Szwargulski, F Werner, N Gdaniec, M Boberg, F Griese, M Möddel, P Ludewig, D van de Ven and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it, 292 citations in OpenAlex.

  1. Pooled it
  2. Verification and validation in canine cadaver of an MPI-integrable RF head coil for magnetic particle hyperthermia.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026
    Article
  3. Design, verification and validation of a spatially confined magnetic nanoparticle thermal therapy device for conformal thermal dose contouring.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026
    Article
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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

M GraeserSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany. matthias.graeser@tuhh.de.ORCID http://orcid.org/0000-0003-1472-5988
F ThiebenSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0002-2890-5288
P SzwargulskiSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0003-2563-9006
F WernerSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.
N GdaniecSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0002-5060-0683
M BobergSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0003-3419-7481
F GrieseSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0003-3309-9783
M MöddelSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0002-4737-7863
P LudewigDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.
D van de VenSensing and Inspection Technologies GmbH, 50354, Huerth, Germany.
O M WeberPhilips GmbH Market DACH, 22335, Hamburg, Germany.ORCID http://orcid.org/0000-0002-2569-0875
O WoywodeImaging Components, Philips Medical Systems DMC GmbH, 22335, Hamburg, Germany.
B GleichResearch Laboratories, Philips GmbH Innovative Technologies, 22335, Hamburg, Germany.
T KnoppSection for Biomedical Imaging, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.ORCID http://orcid.org/0000-0002-1589-8517
Universität Hamburg · DEPhilips (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determining the brain perfusion is an important task for diagnosis of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis, there is a high risk of restenosis or rebleeding such that patients need intense attention in the days after treatment. Within this work, we present a diagnostic tomographic imager that allows access to brain perfusion quantitatively in short intervals. The device is based on the magnetic particle imaging technology and is designed for human scale. It is highly sensitive and allows the detection of an iron concentration of 263 pmol

Indexed as

BrainCerebrovascular DisordersContrast MediaDextransHumansIntensive Care UnitsIntracranial HemorrhagesMagneticsMagnetite NanoparticlesNeuroimagingParticle SizePhantoms, ImagingStrokeTomographyContrast MediaDextransferumoxidesMagnetite Nanoparticles

Identifiers

PMID31028253
PMCPMC6486595
OpenAlexW2897138438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.