Evidence map›Paper›PMID 31028212›Full record

Trial reportIn vivo (Athens, Greece)

Effectiveness of a 12-month Exercise Intervention on Physical Activity and Quality of Life of Breast Cancer Survivors; Five-year Results of the BREX-study.

Heidi Penttinen, Meri Utriainen, Pirkko-Liisa Kellokumpu-Lehtinen, Jani Raitanen, Harri Sievänen, Riku Nikander, Carl Blomqvist, Riikka Huovinen, Leena Vehmanen, Tiina Saarto

Abstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  3. Patient attitudes and experiences towards exercise during oncological treatment. A qualitative systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  6. Long-term effects of exercise interventions on physical activity in breast cancer patients: a systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Heidi PenttinenHelsinki University Hospital, Comprehensive Cancer Center, and Faculty of Medicine, University of Helsinki, Helsinki, Finland heidi.penttinen@fimnet.fi.
Meri UtriainenHelsinki University Hospital, Comprehensive Cancer Center, and Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Pirkko-Liisa Kellokumpu-LehtinenDepartment of Oncology, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Jani RaitanenUKK Institute for Health Promotion Research, Tampere, Finland.
Harri SievänenUKK Institute for Health Promotion Research, Tampere, Finland.
Riku NikanderUKK Institute for Health Promotion Research, Tampere, Finland.
Carl BlomqvistHelsinki University Hospital, Comprehensive Cancer Center, and Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Riikka HuovinenDepartment of Oncology, Turku University Hospital and Faculty of Medicine, University of Turku, Turku, Finland.
Leena VehmanenHelsinki University Hospital, Comprehensive Cancer Center, and Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Tiina SaartoHelsinki University Hospital, Comprehensive Cancer Center, and Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThis is a report of the 5-year quality of life (QoL) findings of the BREX-study (n=444). PATIENTS AND

methodsA 12-month exercise intervention was arranged shortly after adjuvant treatments. Physical activity (PA) was assessed by PA diary, physical performance by a 2- km walking test, QoL by the EORTC QLQC30 and BR-23 questionnaires, fatigue by the FACIT-Fatigue scale and depression by the Beck's 13-item depression scale (BDI).

resultsParticipants who improved their PA from baseline to 5-year follow-up were more likely to improve their global health score (RRR=1.02, p=0.016), physical (RRR=1.02, p=0.009), social (RRR=1.03, p=0.013), role functioning (RRR=1.03, p=0.005), and fatigue (RRR=1.02, p=0.002). An improved 2-km walking test was associated to improved global health, physical and role functioning, body image, future perspectives, and fatigue (p=0.011, p<0.001, p=0.001, p=0.021, p=0.012 and p=0.003). No significant difference between the groups was found.

conclusionImprovement in PA or physical performance yields a positive change in QoL of breast cancer patients.

Indexed as

Breast NeoplasmsCancer SurvivorsExerciseExercise TherapyQuality of LifeAdultAgedFemaleHumansMiddle AgedPatient Outcome AssessmentBreast cancerexercisequality of liferehabilitation

Identifiers

PMID31028212
PMCPMC6559915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.