Evidence map›Paper›PMID 31028184›Full record

ArticleIn vivo (Athens, Greece)

Amelioration of Amyotrophic Lateral Sclerosis in SOD1

Michael W Epperly, Renee Fisher, Lora Rigatti, Simon Watkins, Xichen Zhang, Wen Hou, Donna Shields, Darcy Franicola, Hulya Bayir, Hong Wang and 5 more

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Anti-Inflammatory Effects of MiyakoInternational journal of molecular sciences · 2023
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michael W EpperlyDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Renee FisherDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Lora RigattiDivision of Laboratory Animal Resources (DLAR), University of Pittsburgh, Pittsburgh, PA, U.S.A.
Simon WatkinsDepartment of Cell Biology and Center for Images, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Xichen ZhangDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Wen HouDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Donna ShieldsDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Darcy FranicolaDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Hulya BayirDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Hong WangDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Stephanie ThermozierDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Andrew HendersonDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A.
Christopher DonnellyDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Peter WipfDepartment of Chemistry, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Joel S GreenbergerDepartment of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, U.S.A. greenbergerjs@upmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAmino Acid SubstitutionAmyotrophic Lateral SclerosisAnimalsBlood-Brain BarrierBone Marrow TransplantationCell DifferentiationDisease Models, AnimalGene ExpressionGraft SurvivalHematopoiesisMiceMice, TransgenicMicrogliaRadiation ToleranceSuperoxide Dismutase-1Superoxide Dismutase-1ALSmarrow originspinal cord M2 cellsTotal body irradiation

Identifiers

PMID31028184
PMCPMC6559904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.