Evidence map›Paper›PMID 31028137›Full record

ArticleBioscience reports2019

Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach.

Mohd Amir, Vijay Kumar, Taj Mohammad, Ravins Dohare, Md Tabish Rehman, Mohamed F Alajmi, Afzal Hussain, Faizan Ahmad, Md Imtaiyaz Hassan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Mohd AmirCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India.
Vijay KumarAmity Institute of Neuropsychology & Neurosciences, Amity University, Noida, UP 201303, India.ORCID 0000-0002-3621-5025
Taj MohammadCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India.
Ravins DohareCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India.
Md Tabish RehmanDepartment of Pharmacognosy College of Pharmacy, King Saud University, Riyadh 11451, K.S.A.
Mohamed F AlajmiDepartment of Pharmacognosy College of Pharmacy, King Saud University, Riyadh 11451, K.S.A.
Afzal HussainDepartment of Pharmacognosy College of Pharmacy, King Saud University, Riyadh 11451, K.S.A.
Faizan AhmadCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India.
Md Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India mihassan@jmi.ac.in.ORCID 0000-0002-3663-4940
Jamia Millia Islamia · INKing Saud University · SAAmity University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TEN1 protein is a key component of CST complex, implicated in maintaining the telomere homeostasis, and provides stability to the eukaryotic genome. Mutations in

Indexed as

MutationPolymorphism, Single NucleotideHumansProtein Conformation, alpha-HelicalStructure-Activity RelationshipTelomere-Binding ProteinsTelomere-Binding ProteinsTen1 protein, humanOB fold proteinPathogenic mutationsSequence analysisSNPStructural genomics

Identifiers

PMID31028137
PMCPMC6522806
OpenAlexW2952023095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.