Evidence map›Paper›PMID 31028135›Full record

Trial reportBioscience reports2019

ssExpression level of GAS6-mRNA influences the prognosis of acute myeloid leukemia patients with allogeneic hematopoietic stem cell transplantation.

Xinrui Yang, Jinlong Shi, Xinpei Zhang, Gaoqi Zhang, Jilei Zhang, Siyuan Yang, Jing Wang, Xiaoyan Ke, Lin Fu

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xinrui YangDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Jinlong ShiDepartment of Biomedical Engineering, Chinese PLA General Hospital, Beijing 100853, China.
Xinpei ZhangDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Gaoqi ZhangDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Jilei ZhangDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Siyuan YangDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Jing WangDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Xiaoyan KeDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China.
Lin FuDepartment of Hematology and Lymphoma Research Center, Peking University, Third Hospital, Beijing 100191, China fulin022@126.com xiaoyank@yahoo.com.ORCID 0000-0002-2416-7572
Peking University · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As high expression level of growth arrest-specific 6 (GAS6) had an adverse effect on prognosis in acute myeloid leukemia (AML) patients, it is interesting to reveal the relationship between GAS6-mRNA level and the survival condition of AML patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). We screened The Cancer Genome Atlas database and found 71 AML patients with GAS6-mRNA expression and received allo-HSCT treatments. We divided them into two groups based on the median expression of GAS6-mRNA. Patients with GAS6-mRNA

Indexed as

Gene Expression Regulation, LeukemicHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAgedAllograftsDisease-Free SurvivalFemaleGrowth Arrest-Specific Protein 6HumansIntercellular Signaling Peptides and ProteinsMaleMiddle AgedNeoplasm ProteinsRNA, MessengerRNA, NeoplasmSurvival RateGrowth Arrest-Specific Protein 6Intercellular Signaling Peptides and ProteinsNeoplasm ProteinsRNA, MessengerRNA, Neoplasmallo-HSCTAMLGrowth arrest-specific 6next generation sequencingprognosis

Identifiers

PMID31028135
PMCPMC6527924
OpenAlexW2941726065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.