Evidence map›Paper›PMID 31028113›Full record

ArticleGenetics2019

Instability of the Pseudoautosomal Boundary in House Mice.

Andrew P Morgan, Timothy A Bell, James J Crowley, Fernando Pardo-Manuel de Villena

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  11. Generation and Comparative Analysis of anNature cardiovascular research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Andrew P MorganDepartment of Genetics, University of North Carolina, Chapel Hill, North Carolina 27514 andrew.parker.morgan@gmail.com fernando@med.unc.edu.ORCID 0000-0003-1942-4543
Timothy A BellDepartment of Genetics, University of North Carolina, Chapel Hill, North Carolina 27514.
James J CrowleyDepartment of Genetics, University of North Carolina, Chapel Hill, North Carolina 27514.
Fernando Pardo-Manuel de VillenaDepartment of Genetics, University of North Carolina, Chapel Hill, North Carolina 27514 andrew.parker.morgan@gmail.com fernando@med.unc.edu.ORCID 0000-0002-5738-5795
University of North Carolina at Chapel Hill · USKarolinska Institutet · SEUNC Lineberger Comprehensive Cancer Center

Funding

Resource Section - Core 001U42OD010924 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Fernando Pardo-Manuel de Villena · 2012 to 2026
$24.5M
An Interdisciplinary program for systems genomics of complex behaviorsP50MH090338 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARDO-MANUEL DE VILLENA, FERNANDO · 2009 to 2010
$6.0M
An Interdisciplinary program for systems genomics of complex behaviorsP50HG006582 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARDO-MANUEL DE VILLENA, FERNANDO · 2011 to 2013
$2.6M
Collaborative Cross: A system genetics approach to the study of male infertilityR01HD065024 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI O'BRIEN, DEBORAH A., PARDO-MANUEL DE VILLENA, FERNANDO · 2010 to 2014
$1.7M
Systems Genetics of Fluoxetine-Induced Neurogenesis and Antidepressant ResponseK01MH094406 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CROWLEY, JAMES JOSEPH · 2012 to 2015
$588k
Effect of paternal age on mutational burden and behavior in miceR21MH096261 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARDO-MANUEL DE VILLENA, FERNANDO · 2012 to 2013
$400k
Effects of advanced paternal age on germline genome stabilityF30MH103925 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, ANDREW PARKER · 2014 to 2017
$151k
NHGRI NIH HHS P50 HG006582NICHD NIH HHS R01 HD065024NIH HHS U42 OD010924NIMH NIH HHS F30 MH103925NIMH NIH HHS K01 MH094406NIMH NIH HHS P50 MH090338NIMH NIH HHS R21 MH096261
6 · The paper itself

Abstract

Faithful segregation of homologous chromosomes at meiosis requires pairing and recombination. In taxa with dimorphic sex chromosomes, pairing between them in the heterogametic sex is limited to a narrow interval of residual sequence homology known as the pseudoautosomal region (PAR). Failure to form the obligate crossover in the PAR is associated with male infertility in house mice (

Indexed as

Chromosome MappingAnimalsEvolution, MolecularFemaleMaleMeiosisMicePseudoautosomal RegionsRecombination, GeneticSpecies SpecificityX ChromosomeY Chromosomemeiosispseudoautosomal regionrecombinationsex chromosome evolution

Identifiers

PMID31028113
PMCPMC6553833
OpenAlexW2915306247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.