Evidence map›Paper›PMID 31027378›Full record

ArticleJournal of clinical medicine2019

Microangiopathy in Naifold Videocapillaroscopy and Its Relations to sE- Selectin, Endothelin-1, and hsCRP as Putative Endothelium Dysfunction Markers among Adolescents with Raynaud's Phenomenon.

Stanislaw Gorski, Marta Bartnicka, Anna Citko, Beata Żelazowska-Rutkowska, Konrad Jablonski, Anna Gorska

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stanislaw GorskiDepartment of Medical Education, Jagiellonian University Medical College, 31-530 Krakow, Poland. stanislaw.gorski@uj.edu.pl.ORCID 0000-0002-1740-4082
Marta BartnickaDepartment of Family Medicine, Medical University of Bialystok, 15-054 Bialystok, Poland. martawozniak@o2.pl.
Anna CitkoOutpatient Clinic, Bialystok Children's Clinical Hospital of L. Zamenhof, Medical University of Bialystok, 15-274 Bialystok, Poland. anka234@gmail.com.
Beata Żelazowska-RutkowskaDepartment of Pediatric Laboratory Diagnostics, Medical University of Bialystok, 15-276 Bialystok, Poland. beata.zelazowska@umb.edu.pl.
Konrad JablonskiDepartment of Medical Education, Jagiellonian University Medical College, 31-530 Krakow, Poland. konrad.jablonski@uj.edu.pl.
Anna GorskaDepartment of Family Medicine, Medical University of Bialystok, 15-054 Bialystok, Poland. agorska50@wp.pl.

Funding

Uniwersytet Medyczny w Bialymstoku N/ST/2B18/001/3331
6 · The paper itself

Abstract

The aim of this study was to analyze the relationship between the qualitative abnormalities on nailfold videocapillaroscopy (NVC), and the concentrations of selected biomarkers (sE-selectin, endothelin-1, high-sensitivity c-reactive protein (hsCRP)) and lipid metabolism parameters in children and adolescents with Raynaud's phenomenon (RP). Raynaud's phenomenon, to assess whether nailfold capillary changes may reflect the degree of systemic blood vessel abnormalities. The study group included 66 patients (34 undifferentiated-uRP and 32 secondary-sRP) aged 6-19 years and the control group. In both groups, NVC was performed and the selected biomarkers were measured (sE-selectin, endothelin-1, hsCRP) and lipid profile. Endothelin-1, sE-selectin and hsCRP concentrations in patients from both RP groups were significantly higher; concentration of HDL fraction was significantly lower compared with the control group. The analysis of multiple linear regression demonstrated that megacapillaries most strongly determine the sE-selectin value (

Indexed as

adolescentsatherosclerosisbiomarkerschildrenendothelin dysfunctionlipid profileRaynaud’s phenomenonvideocapillaroscopy

Identifiers

PMID31027378
PMCPMC6572411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.