Evidence map›Paper›PMID 31027298›Full record

ReviewMolecules (Basel, Switzerland)2019

Modern Methods of Sample Preparation for the Analysis of Oxylipins in Biological Samples.

Ivan Liakh, Alicja Pakiet, Tomasz Sledzinski, Adriana Mika

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ivan LiakhDepartment of Pharmaceutical Biochemistry, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland. liakh_ivan@mail.ru.
Alicja PakietDepartment of Environmental Analysis, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland. alicjapakiet@gmail.com.
Tomasz SledzinskiDepartment of Pharmaceutical Biochemistry, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland. tsledz@gumed.edu.pl.
Adriana MikaDepartment of Pharmaceutical Biochemistry, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland. adrianamika@tlen.pl.
Gdańsk Medical University · PLUniversity of Gdańsk · PL

Funding

Narodowe Centrum Nauki 2016/21/D/NZ5/00219Narodowe Centrum Nauki 2016/22/E/NZ4/00665
6 · The paper itself

Abstract

Oxylipins are potent lipid mediators derived from polyunsaturated fatty acids, which play important roles in various biological processes. Being important regulators and/or markers of a wide range of normal and pathological processes, oxylipins are becoming a popular subject of research; however, the low stability and often very low concentration of oxylipins in samples are a significant challenge for authors and continuous improvement is required in both the extraction and analysis techniques. In recent years, the study of oxylipins has been directly related to the development of new technological platforms based on mass spectrometry (LC-MS/MS and gas chromatography-mass spectrometry (GC-MS)/MS), as well as the improvement in methods for the extraction of oxylipins from biological samples. In this review, we systematize and compare information on sample preparation procedures, including solid-phase extraction, liquid-liquid extraction from different biological tissues.

Indexed as

Chromatography, LiquidGas Chromatography-Mass SpectrometryLiquid-Liquid ExtractionOxylipinsSolid Phase ExtractionTandem Mass SpectrometryOxylipinsbiological samplesliquid–liquid extractionoxylipinsprotein precipitationsample preparationsolid-phase extraction

Identifiers

PMID31027298
PMCPMC6515351
OpenAlexW2940841976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.