Evidence map›Paper›PMID 31027182›Full record

ArticleCells2019

Chronic Hepatitis C Virus Infection Impairs M1 Macrophage Differentiation and Contributes to CD8

Faria Ahmed, Andrea Ibrahim, Curtis L Cooper, Ashok Kumar, Angela M Crawley

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Liver Macrophages in the Pathogenesis of Viral Hepatitis.Current issues in molecular biology · 2026
    Review
  2. Article
  3. Macrophage ferroptosis in hematologic malignancies: emerging mechanisms and therapeutic implications.Apoptosis : an international journal on programmed cell death · 2026
    Review
  4. Article
  5. Review
  6. Article
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  10. Article
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Macrophage regulation of graft-World journal of clinical cases · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Faria AhmedDepartment of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. fahme097@uottawa.ca.ORCID 0000-0002-0456-4204
Andrea IbrahimDepartment of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. andibrahim@ohri.ca.
Curtis L CooperClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada. ccooper@toh.ca.ORCID 0000-0002-3368-3499
Ashok KumarDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. akumar@uottawa.ca.
Angela M CrawleyDepartment of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. acrawley@ohri.ca.ORCID 0000-0002-7453-7922
University of Ottawa · CA

Funding

CIHR NHC-142832
6 · The paper itself

Abstract

Chronic hepatitis C virus (HCV) infection causes generalized CD8

Indexed as

AdultCD8-Positive T-LymphocytesCell DifferentiationCells, CulturedCytokinesFemaleHepacivirusHepatitis CHepatitis C, ChronicHumansInterferon-gammaLiver CirrhosisMacrophage ActivationMacrophagesMaleMiddle AgedCytokinesInterferon-gammaCD8+ T-cellshepatitis C virusinterferon-γmacrophagesmonocyte-derived macrophages

Identifiers

PMID31027182
PMCPMC6523920
OpenAlexW2941083042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.