ArticleMedical image analysis2019
Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes.
Article in Medical image analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Medical image analysis on left atrial LGE MRI for atrial fibrillation studies: A review.Medical image analysis · 2022Pooled it
- Multimodal Characterization of Atrial Fibrillation: From Patient-Specific Anatomy and Electrophysiology to Standardized Atrial Mapping.Tomography (Ann Arbor, Mich.) · 2026Review
- Transmural heterogeneity in 3D fibrosis distribution is associated with endo-epicardial electrical dyssynchrony in persistent atrial fibrillation.The Journal of physiology · 2026Article
- Analysis of the Effect of Anatomical Variability on Atrial Fibrillation Dynamics Through a Novel Framework for Personalised Atrial Model Generation.Annals of biomedical engineering · 2026Article
- Relationships between three-dimensional fibrosis distribution, atrial adiposity, and voltage abnormalities associated with persistent atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Rapid calibration of atrial electrophysiology models using Gaussian process emulators in the ensemble Kalman filter.Scientific reports · 2026Article
- Weaving the Digital Tapestry: Methods for Emulating Cohorts of Cardiac Digital Twins Using Gaussian Processes.Annals of biomedical engineering · 2026Article
- Automated generation of ablation lesion masks: a unison of electro and optic flow mapping for persistent AF virtual cohorts.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- An efficient end-to-end computational framework for the generation of ECG calibrated volumetric models of human atrial electrophysiology.Medical image analysis · 2026Article
- The effect of clinically relevant changes in extracellular electrolyte concentrations on human atrial arrhythmias.Communications medicine · 2025Article
- A Left Atrial Positioning System to Enable Follow-up and Cohort Studies.IEEE transactions on bio-medical engineering · 2025Article
- Regional heterogeneity in left atrial stiffness impacts passive deformation in a cohort of patient-specific models.PLoS computational biology · 2025Article
- Predicting arrhythmia recurrence post-ablation in atrial fibrillation using explainable machine learning.Communications medicine · 2025Article
- Cardiac digital twins: a tool to investigate the function and treatment of the diabetic heart.Cardiovascular diabetology · 2025Review
- Rhythm control benefits left ventricular function compared with rate control in patients with atrial fibrillation: A computational study.Heart rhythm O2 · 2025Article
- Design and Validation of a High-Fidelity Left Atrial Cardiac Simulator for the Study and Advancement of Left Atrial Appendage Occlusion.Cardiovascular engineering and technology · 2025Article
- Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025Review
- Digital twins enable stratification of persistent atrial fibrillation patients for ablation diminishing unnecessary heart damage.NPJ digital medicine · 2025Article
- Defining myocardial fiber bundle architecture in atrial digital twins.Computers in biology and medicine · 2025Article
- A computational study on the influence of antegrade accessory pathway location on the 12-lead electrocardiogram in Wolff-Parkinson-White syndrome.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Integrating spatial information about atrial physiology and anatomy in a single patient from multimodal datasets, as well as generalizing these data across patients, requires a common coordinate system. In the atria, this is challenging due to the complexity and variability of the anatomy. We aimed to develop and validate a Universal Atrial Coordinate (UAC) system for the following applications: combination and assessment of multimodal data; comparison of spatial data across patients; 2D visualization; and construction of patient specific geometries to test mechanistic hypotheses. Left and right atrial LGE-MRI data were segmented and meshed. Two coordinates were calculated for each atrium by solving Laplace's equation, with boundary conditions assigned using five landmark points. The coordinate system was used to map spatial information between atrial meshes, including scalar fields measured using different mapping modalities, and atrial anatomic structures and fibre directions from a reference geometry. Average error in point transfer from a source mesh to a destination mesh and back again was less than 0.1 mm for the left atrium and 0.02 mm for the right atrium. Patient specific meshes were constructed using the coordinate system and phase singularity density maps from arrhythmia simulations were visualised in 2D. In conclusion, we have developed a universal atrial coordinate system allowing automatic registration of imaging and electroanatomic mapping data, 2D visualisation, and patient specific model creation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.