Evidence map›Paper›PMID 31026243›Full record

ArticleJournal of hypertension2019

Predictors for progressions of brachial-ankle pulse wave velocity and carotid intima-media thickness over a 12-year follow-up: Hanzhong Adolescent Hypertension Study.

Yang Wang, Yue Yuan, Wei-Hua Gao, Yu Yan, Ke-Ke Wang, Peng-Fei Qu, Jia-Wen Hu, Chao Chu, Li-Jun Wang, Ke Gao and 8 more

Abstract read
In one paragraph

Article in Journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Pulse Wave Velocity Progression Determinants: No Significant Association with Novel Lipids Parameter.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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  17. State of the Art Review: Brachial-Ankle PWV.Journal of atherosclerosis and thrombosis · 2020
    Review
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  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yang WangDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Yue YuanDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Wei-Hua GaoDepartment of Cardiovascular Medicine, Xi'an No.1 Hospital.
Yu YanDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Ke-Ke WangDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Peng-Fei QuAssisted Reproduction Center, Northwest Women and Children's Hospital, Xi'an, Shaanxi.
Jia-Wen HuDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Chao ChuDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Li-Jun WangDepartment of Cardiology, Affiliated Zhongshan Hospital, Dalian University, Dalian, Liaoning.
Ke GaoDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Yue-Yuan LiaoDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Chen ChenDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Jing-Tao XuDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Qiong MaDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Wen-Ling ZhengDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Hao LiDepartment of Critical Care Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zu-Yi YuanDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.
Jian-Jun MuDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAtherosclerotic diseases are the leading cause of death worldwide. This study aimed to investigate the predictors of brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (CIMT) progression in a Chinese cohort over a 12-year follow-up period and to determine whether these predictors differ by follow-up time.

methodsA total of 202 participants were recruited from a previously established cohort in Shaanxi Province, China. Both baPWV and CIMT were measured in 2013 and 2017. Multivariable regression was used to determine the predictors of CIMT and baPWV progression.

resultsMen had higher CIMT and baPWV and a higher rate of CIMT progression during two follow-ups than women. A 4-year change in SBP was associated with baPWV progression, whereas a 12-year change in DBP was associated with baPWV progression. The increased progression of baPWV presented a linear trend when subgrouping all the participants according to SBP and DBP changes over 4 and 12 years, respectively. In addition, heart rate (HR) change over 4 and 12 years was consistently associated with CIMT progression, and a linear trend was also seen when subgrouping the population.

conclusionOur study demonstrated that SBP and DBP contributed differently in different stages to the progression of arterial stiffness in this Chinese cohort. Moreover, HR was consistently involved in the increased progression of CIMT in all periods. These findings underline the importance of early detection and control of blood pressure and resting HR for the prevention of arterial stiffness progression.

Indexed as

Blood PressureCarotid Intima-Media ThicknessPulse Wave AnalysisAdultAnkle Brachial IndexAsian PeopleAtherosclerosisChinaCohort StudiesDisease ProgressionFemaleFollow-Up StudiesHeart RateHumansHypertensionMale

Identifiers

PMID31026243
PMCPMC6513272

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.