ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2019
Alcohol Intake and Risk of Lethal Prostate Cancer in the Health Professionals Follow-Up Study.
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Consumption of Red Versus White Wine and Cancer Risk: A Meta-Analysis of Observational Studies.Nutrients · 2025Pooled it
- Pooled it
- Pooled it
- Alcohol consumption among patients diagnosed with genitourinary cancers.BJUI compass · 2025Article
- Multivitamin Use After Prostate Cancer Diagnosis Is Associated with Lower Risk of Recurrence: A Prospective Cohort Study from the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE).European urology oncology · 2025Observational
- Evaluating recommendation-based dietary and physical activity strategies for prostate cancer prevention: a target trial emulation in the Health Professionals Follow-up Study.American journal of epidemiology · 2025Article
- Review
- Identifying modifiable risk factors to prevent aggressive colorectal cancer.International journal of cancer · 2024Article
- Review
- Modifiable risk factors for subsequent lethal prostate cancer among men with an initially negative prostate biopsy.British journal of cancer · 2023Article
- Review
- Post-diagnostic health behaviour scores and risk of prostate cancer progression and mortality.British journal of cancer · 2023Article
- Association of Diet Quality with Metabolic (Dysfunction) Associated Fatty Liver Disease in Veterans in Primary Care.Nutrients · 2023Article
- Racism Does Not Cause Prostate Cancer, It Causes Prostate Cancer Death.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023Article
- Patterns of cigarette smoking and alcohol drinking among Canadian adults with cancer in a contemporary national cohort.Journal of cancer survivorship : research and practice · 2023Article
- Post-diagnostic health behaviour scores in relation to fatal prostate cancer.British journal of cancer · 2022Article
- Article
- Alcohol and Prostate Cancer: Time to Draw Conclusions.Biomolecules · 2022Review
- Somatic mutational profiles and germline polygenic risk scores in human cancer.Genome medicine · 2022Article
- Regular Aspirin Use and Mortality in Patients with Multiple Myeloma.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
12 authors.
Funding
Abstract
purposeIt is unknown whether alcohol intake is associated with the risk of lethal (metastatic or fatal) prostate cancer. We examine (1) whether alcohol intake among men at risk of prostate cancer is associated with diagnosis of lethal prostate cancer and (2) whether intake among men with nonmetastatic prostate cancer is associated with metastasis or death.
methodsThis prospective cohort study uses the Health Professionals Follow-Up Study (1986 to 2012). Our analysis of alcohol intake among men at risk of prostate cancer included 47,568 cancer-free men. Our analysis of alcohol intake among men with prostate cancer was restricted to 5,182 men diagnosed with nonmetastatic prostate cancer during follow-up. We examine the association of total alcohol, red and white wine, beer, and liquor with lethal prostate cancer and death. Multivariate Cox proportional hazards regression estimated hazard ratios (HRs) and 95% CIs.
resultsAlcohol drinkers had a lower risk of lethal prostate cancer (any
conclusionCancer-free men who consumed alcohol had a slightly lower risk of lethal prostate cancer compared with abstainers. Among men with prostate cancer, red wine was associated with a lower risk of progression to lethal disease. These observed associations merit additional study but provide assurance that moderate alcohol consumption is safe for patients with prostate cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.