Evidence map›Paper›PMID 31025949›Full record

ArticleJMIR mental health2019

Use of a Mobile Phone App to Treat Depression Comorbid With Hypertension or Diabetes: A Pilot Study in Brazil and Peru.

Paulo Menezes, Julieta Quayle, Heloísa Garcia Claro, Simone da Silva, Lena R Brandt, Francisco Diez-Canseco, J Jaime Miranda, LeShawndra N Price, David C Mohr, Ricardo Araya

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR mental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06658756 (Implementation of Internet-Based Psychotherapy for Obsessive-Compulsive Disorder), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06658756 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Implementation of Internet-Based Psychotherapy for Obsessive-Compulsive Disorder (OCD) in Primary Health Care in Two Cities in the State of São Paulo

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2025 to 2028Enrolled140ConditionsObsessive-Compulsive DisorderArmsinternet-CBT
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.

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  13. Text Messages for Depression, Anxiety and Alcohol Abuse Therapy-Are Construction Guidelines Needed?International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Paulo Menezes *Population Mental Health Research Centre, Department of Preventive Medicine, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-6330-3314
Julieta Quayle *Population Mental Health Research Centre, Department of Preventive Medicine, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-3325-0922
Heloísa Garcia Claro *Population Mental Health Research Centre, Department of Preventive Medicine, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1504-7074
Simone da Silva *Population Mental Health Research Centre, Department of Preventive Medicine, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-2460-3557
Lena R Brandt *Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0001-7800-8473
Francisco Diez-Canseco *Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0002-7611-8190
J Jaime Miranda *Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0002-4738-5468
LeShawndra N Price *National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States.ORCID http://orcid.org/0000-0003-2632-8605
David C Mohr *Center for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID http://orcid.org/0000-0002-5443-7596
Ricardo Araya *Centre for Global Mental Health and Primary Care Research, Health Service and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.ORCID http://orcid.org/0000-0002-0420-5148
Universidade de São Paulo · BRUniversidad Peruana Cayetano Heredia · PEKing's College London · GBNational Institutes of Health · USNorthwestern University · US

Funding

Latin America Treatment & Innovation Network in Mental Health (LATIN-MH)U19MH098780 · NIMH · FUNDACAO FACULDADE DE MEDICINA · PI ARAYA, RICARDO, MENEZES, PAULO ROSSI · 2013 to 2017
$2.7M
Medical Research Council MR/M007405/1NIMH NIH HHS U19 MH098780
6 · The paper itself

Abstract

backgroundDepression is underdiagnosed and undertreated in primary health care. When associated with chronic physical disorders, it worsens outcomes. There is a clear gap in the treatment of depression in low- and middle-income countries (LMICs), where specialists and funds are scarce. Interventions supported by mobile health (mHealth) technologies may help to reduce this gap. Mobile phones are widely used in LMICs, offering potentially feasible and affordable alternatives for the management of depression among individuals with chronic disorders.

objectiveThis study aimed to explore the potential effectiveness of an mHealth intervention to help people with depressive symptoms and comorbid hypertension or diabetes and explore the feasibility of conducting large randomized controlled trials (RCTs).

methodsEmotional Control (CONEMO) is a low-intensity psychoeducational 6-week intervention delivered via mobile phones and assisted by a nurse for reducing depressive symptoms among individuals with diabetes or hypertension. CONEMO was tested in 3 pilot studies, 1 in São Paulo, Brazil, and 2 in Lima, Peru. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9) at enrollment and at 6-week follow-up.

resultsThe 3 pilot studies included a total of 66 people. Most participants were females aged between 41 and 60 years. There was a reduction in depressive symptoms as measured by PHQ-9 in all pilot studies. In total, 58% (38/66) of the participants reached treatment success rate (PHQ-9 <10), with 62% (13/21) from São Paulo, 62% (13/21) from the first Lima pilot, and 50% (12/24) from the second Lima pilot study. The intervention, the app, and the support offered by the nurse and nurse assistants were well received by participants in both settings.

conclusionsThe intervention was feasible in both settings. Clinical data suggested that CONEMO may help in decreasing participants' depressive symptoms. The findings also indicated that it was possible to conduct RCTs in these settings.

Indexed as

depressionfeasibility studymHealthPHQ-9pilot study

Identifiers

PMID31025949
PMCPMC6658291
OpenAlexW2913551388

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.