Evidence map›Paper›PMID 31025558›Full record

ArticleJournal of biomedical optics2019

Comparison of tissue dispersion measurement techniques based on optical coherence tomography.

Christos Photiou, Costas Pitris

Abstract readComparative Study
In one paragraph

Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christos PhotiouUniversity of Cyprus, KIOS Research and Innovation Center of Excellence, Department of Electrical an, Cyprus.
Costas PitrisUniversity of Cyprus, KIOS Research and Innovation Center of Excellence, Department of Electrical an, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of dispersion on optical coherence tomography (OCT) images have long been documented. The imbalance of spectral broadening, caused by dispersion mismatches in the two arms of the OCT interferometer, can result in significant resolution degradation. Efforts to correct this phenomenon have resulted in improved image quality using various techniques. However, dispersion is also present and varies in tissues. As a result, group velocity dispersion (GVD) can be used to detect changes in tissues and provide useful information for diagnosis. Several methods can be utilized to measure the GVD from OCT images: (i) the degradation of the point spread function (PSF), (ii) the shift (walk-off) between images taken at different wavelengths, (iii) the changes in the second derivative of the spectral phase, as well as two new methods, which do not require a reflector and are applicable in intact tissues, i.e., using (iv) the speckle degradation, and (v) the speckle cross correlation. A systematic, experimental, evaluation of these methods is presented to elucidate the capabilities, the limitations, and the accuracy of each technique when attempting to estimate the GVD in scattering samples. The most precise values were obtained from the estimation of the PSF degradation, whereas using the phase derivative method was only applicable to minimally scattering samples. Speckle broadening appears to be the most robust method for tissue GVD measurements.

Indexed as

Adipose TissueAnimalsGlassInterferometryModels, BiologicalMusclesSwineTomography, Optical Coherencedegradationdispersionmethodsoptical coherence tomographyresolution

Identifiers

PMID31025558
PMCPMC6990061

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.