Evidence map›Paper›PMID 31025487›Full record

ArticleBipolar disorders2019

Psychotic symptoms and suicidal ideation in child and adolescent bipolar I disorder.

Mary E Duffy, Anna R Gai, Megan L Rogers, Thomas E Joiner, Joan L Luby, Paramjit T Joshi, Karen D Wagner, Graham J Emslie, John T Walkup, David Axelson

Open access · greenAbstract read
In one paragraph

Article in Bipolar disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Mary E DuffyDepartment of Psychology, Florida State University, Tallahassee, Florida.ORCID 0000-0002-7045-699X
Anna R GaiDepartment of Psychology, Florida State University, Tallahassee, Florida.ORCID 0000-0001-9329-1641
Megan L RogersDepartment of Psychology, Florida State University, Tallahassee, Florida.ORCID 0000-0002-4969-7035
Thomas E JoinerDepartment of Psychology, Florida State University, Tallahassee, Florida.ORCID 0000-0001-6798-9085
Joan L LubyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Paramjit T JoshiDepartment of Psychiatry, University of California, Irvine, California.
Karen D WagnerDepartment of Psychiatry, University of Texas Medical Branch, Galveston, Texas.
Graham J EmslieDivision of Child and Adolescent Psychiatry, Children's Medical Center, Dallas, Texas.
John T WalkupDepartment of Psychiatry, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
David AxelsonNationwide Children's Hospital Research Institute, The Ohio State University College of Medicine, Columbus, Ohio.ORCID 0000-0002-1348-0707
Florida State University · USChildren's Medical Center · USLurie Children's Hospital · USNationwide Children's Hospital · USThe University of Texas Medical Branch at Galveston · USUniversity of California, Irvine · USWashington University in St. Louis · US

Funding

Treatment of Early Age Mania (TEAM)U01MH064846 · NIMH · WASHINGTON UNIVERSITY · PI GELLER, BARBARA · 2002 to 2008
$4.8M
Treatment of Early Age Mania StudyU01MH064869 · NIMH · JOHNS HOPKINS UNIVERSITY · PI RIDDLE, MARK A · 2002 to 2008
$3.3M
Treatment of Early-Age ManiaU01MH064851 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AXELSON, DAVID A · 2002 to 2008
$2.7M
Treatment of Early Age ManiaU01MH064850 · NIMH · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WAGNER, KAREN D · 2002 to 2008
$2.7M
Treatment of Early Age Mania (TEAM)U01MH064887 · NIMH · CHILDREN'S RESEARCH INSTITUTE · PI JOSHI, PARAMJIT T. · 2002 to 2008
$2.6M
Treatment of Early Age Mania (TEAM)U01MH064868 · NIMH · WASHINGTON UNIVERSITY · PI LUBY, JOAN L. · 2002 to 2008
$2.4M
METHODOLOGIES FOR TREATMENT STRATEGIESR01MH051481 · NIMH · STANFORD UNIVERSITY · PI LAVORI, PHILIP WILLIAM · 1995 to 2014
$2.3M
Treatment of Early Age Mania (TEAM)U01MH064911 · NIMH · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI EMSLIE, GRAHAM J. · 2002 to 2003
$777k
NIMH NIH HHS R01 MH051481NIMH NIH HHS U01 MH064846NIMH NIH HHS U01 MH064850NIMH NIH HHS U01 MH064851NIMH NIH HHS U01 MH064868NIMH NIH HHS U01 MH064869NIMH NIH HHS U01 MH064887NIMH NIH HHS U01 MH064911
6 · The paper itself

Abstract

objectivesThe purpose of this study was to explore associations between specific types of hallucinations and delusions and suicidal ideation in a sample of children and adolescents with bipolar I disorder.

methodsParticipants (N = 379) were children and adolescents aged 6-15 years (M = 10.2, SD = 2.7) with DSM-IV diagnoses of bipolar I disorder, mixed or manic phase. The study sample was 53.8% female and primarily White (73.6% White, 17.9% Black, and 8.5% Other). Presence and nature of psychotic symptoms, suicidal ideation, and functioning level were assessed through clinician-administered measures. A series of logistic regressions was performed to assess the contribution of each subtype of psychotic symptom to the presence of suicidal ideation above and beyond age, sex, socio-economic status, age at bipolar disorder onset, and global level of functioning.

resultsHallucinations overall, delusions of guilt, and number of different psychotic symptom types were uniquely associated with increased odds of suicidal ideation after accounting for covariates. Other forms of delusions (eg, grandiose) and specific types of hallucinations (eg, auditory) were not significantly uniquely associated with the presence of suicidal ideation.

conclusionsFindings of this study suggest the presence of hallucinations as a whole, delusions of guilt specifically, and having multiple concurrent types of psychotic symptoms are associated with the presence of suicidal ideation in children and adolescents with bipolar I disorder. Psychotic symptom subtypes, as opposed to psychosis as a whole, are an under-examined, potentially important, area for consideration regarding suicidal ideation in pediatric bipolar I disorder.

Indexed as

Bipolar DisorderDelusionsHallucinationsPsychotic DisordersSuicidal IdeationAdolescentChildCorrelation of DataDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleadolescentbipolar disorderchilddelusionshallucinationspsychotic symptomssuicidal ideation

Identifiers

PMID31025487
PMCPMC6597286
OpenAlexW2941716149

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.