Evidence map›Paper›PMID 31025367›Full record

ArticleJournal of medical primatology2019

Effect of maternal baboon (Papio sp.) dietary mismatch in pregnancy and lactation on post-natal offspring early life phenotype.

Cun Li, Susan Jenkins, Hillary F Huber, Peter W Nathanielsz

Open access · greenAbstract read
In one paragraph

Article in Journal of medical primatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Budding baboon blues: the prenatal diet lands a lasting gut punch.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
  3. Maternal Western diet increases inflammatory markers and decreases barrier function of offspring inAmerican journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
  4. The Influence of Diet on Metabolism and Health Across the Lifespan in Nonhuman Primates.Current opinion in endocrine and metabolic research · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cun LiDepartment of Animal Sciences, Texas Pregnancy and Life-course Health Center, University of Wyoming, Laramie, Wyoming.
Susan JenkinsDepartment of Animal Sciences, Texas Pregnancy and Life-course Health Center, University of Wyoming, Laramie, Wyoming.
Hillary F HuberDepartment of Animal Sciences, Texas Pregnancy and Life-course Health Center, University of Wyoming, Laramie, Wyoming.ORCID 0000-0001-9734-427X
Peter W NathanielszDepartment of Animal Sciences, Texas Pregnancy and Life-course Health Center, University of Wyoming, Laramie, Wyoming.
University of Wyoming · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
PARTURITION AND FETAL PRIMATE HYPOTHALAMIC FUNCTIONP01HD021350 · NICHD · UNIVERSITY OF WYOMING · PI JANSSON, THOMAS · 1987 to 2018
$19.9M
Womb to Tomb: Developmental Programming and Aging Interactions in PrimatesU19AG057758 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CLARKE, GEOFFREY DAVID, COX, LAURA A · 2018 to 2024
$13.2M
Developmental Programming by Mismatch of Pre- and Postnatal NutritionR24OD011183 · OD · UNIVERSITY OF WYOMING · PI NATHANIELSZ, PETER W. · 2012 to 2015
$2.9M
Developmental Programming by Mismatch of Pre-and Postnatal NurtitionR24RR031459 · NCRR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI NATHANIELSZ, PETER W., NIJLAND, MARK J · 2011 to 2011
$536k
NCRR NIH HHS R24 RR031459NIA NIH HHS L40 AG064694NICHD NIH HHS P01 HD021350NIH HHS P51 OD011133NIH HHS R24 OD011183
6 · The paper itself

Abstract

backgroundNon-human primate models of developmental programing by maternal mismatch between pregnancy and lactation diets are needed for translation to human programing outcomes. We present baboon offspring morphometry from birth to 3 years, and blood cortisol and adrenocorticotropin (ACTH) from 2 to 24 months.

methodsControl mothers ate chow; mismatch mothers ate 30% less than controls during pregnancy and high-fat high-energy diet through lactation.

resultsMismatch mothers lost weight during pregnancy. At birth, there were trends toward lower weight in mismatch offspring of both sexes (P = 0.06). From 0-3 years, catch-up growth occurred. Mismatch offspring male and female body weight increased faster than controls (P < 0.001). Mismatch female offspring showed greater increase in BMI (P < 0.001) and abdominal circumference (P = 0.008) vs controls. ACTH and cortisol slopes from 2 to 24 months of age were similar between groups in both sexes. Cortisol and ACTH increased after weaning in all groups.

conclusionsMismatch produces sexually dimorphic post-natal growth phenotypes.

Indexed as

Body WeightDiet, High-FatAnimal Nutritional Physiological PhenomenaAnimalsFemaleLactationMalePapioPhenotypePregnancyACTHbabooncatch-up growthcortisoldevelopmental programinghigh-fat dietmaternal nutritionmismatchnon-human primatesundernutrition

Identifiers

PMID31025367
PMCPMC6610582
OpenAlexW2941498877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.