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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Health utility and health-related quality of life of Japanese prostate cancer patients according to progression status measured using EQ-5D-5L and FACT-P.

Hideki Murasawa, Takayuki Sugiyama, Yuki Matsuoka, Takashi Okabe, Amiko Hino, Nobumichi Tanaka, Mikio Sugimoto, Masafumi Oyama, Kiyohide Fujimoto, Shigeo Horie and 2 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Health state utility values by cancer stage: a systematic literature review.The European journal of health economics : HEPAC : health economics in prevention and care · 2021
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. A non-compensatory analysis of quality of life in breast cancer survivors using multivariate hidden Markov modeling.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  10. Factors contributing to the ceiling effect of the EQ-5D-5L: an analysis of patients with prostate cancer judged "no-problems".Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hideki MurasawaDepartment of Life Sciences, Ritsumeikan University, Kusatsu, Japan. h-mura@fc.ritsumei.ac.jp.ORCID http://orcid.org/0000-0003-4897-1239
Takayuki SugiyamaDepartment of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Yuki MatsuokaDepartment of Urology, Faculty of medicine, Kagawa University, Kagawa, Japan.
Takashi OkabeDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Amiko HinoDepartment of Urology, Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Nobumichi TanakaDepartment of Urology, Nara Medical University, Nara, Japan.
Mikio SugimotoDepartment of Urology, Faculty of medicine, Kagawa University, Kagawa, Japan.
Masafumi OyamaDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Kiyohide FujimotoDepartment of Urology, Nara Medical University, Nara, Japan.
Shigeo HorieDepartment of Urology, Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Shinichi NotoDepartment of Health Sciences, Niigata University of Health and Welfare, Niigata, Japan.
Kojiro ShimozumaDepartment of Life Sciences, Ritsumeikan University, Kusatsu, Japan.

Funding

Japan Society for the Promotion of Science JP16K08894Japan Society for the Promotion of Science JP26293116
6 · The paper itself

Abstract

purposeTo obtain health utility data to allow for cost-effectiveness analysis in groups stratified by disease progression along with health-related quality of life (HRQoL) information in Japanese prostate cancer (PC) patients.

methodsIn this cross-sectional observational study, EuroQol-5 Dimension- 5 Level (EQ-5D-5L), EuroQol Visual Analog Scale (EQ-VAS), and Functional Assessment of Cancer Therapy-Prostate (FACT-P) measures were used to examine utility, VAS scores, and disease-specific HRQoL, respectively. Scores obtained were statistically examined for the correlation among measures and domains. Parameter estimates of statistically significant factors were assessed using generalized linear models (GLM).

resultsA total of 380 patients stratified by their disease progression status were analyzed. The numbers (%) of patients in groups stratified as having localized (L), localized progression (LP), distant metastatic (DM), and DM-castration-resistant PC (CRPC) were 275 (72.4), 40 (10.5), 27 (7.1), and 38 (10.0), respectively. EQ-5D-5L mean (standard deviation, SD) scores of L, LP, DM, and DM-CRPC in study participants were 0.87 (0.15), 0.86 (0.15), 0.85 (0.18), and 0.84 (0.17), respectively. The mean (SD) scores assessed by EQ-5D-5L, EQ-VAS, and FACT-P instruments were 0.86 (0.16), 74.6 (16.8), and 110.8 (19.6), respectively. Utility scores correlated well with FACT-P scores. Eastern Cooperative Oncology Group performance status had significant influences on all instruments' scores.

conclusionsWe obtained health utility and HRQoL scores of Japanese PC patients stratified by disease progression in detail. Our results will be useful for establishing cost-effectiveness analyses in Japanese PC settings.

Indexed as

Health StatusAgedCross-Sectional StudiesDisease ProgressionHumansJapanLinear ModelsMaleProstatic NeoplasmsQuality of LifeSurveys and QuestionnairesEQ-5D-5LEQ-VASFACT-PHealth-related quality of life (HRQoL)Prostate cancer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.