Evidence map›Paper›PMID 31025265›Full record

ArticleJournal of neurovirology2019

Immunometabolic phenotype of BV-2 microglia cells upon murine cytomegalovirus infection.

Natalia Kučić, Valentino Rački, Kristina Jurdana, Marina Marcelić, Kristina Grabušić

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Immunometabolic Modulatory Role of Naltrexone in BV-2 Microglia Cells.International journal of molecular sciences · 2021
    Article
  4. Review
  5. Article
  6. CNS Macrophages and Infant Infections.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Natalia KučićDepartment of Physiology and Immunology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20, 51000, Rijeka, Croatia. natalia.kucic@medri.uniri.hr.ORCID 0000-0003-1486-4208
Valentino RačkiDepartment of Physiology and Immunology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20, 51000, Rijeka, Croatia.
Kristina JurdanaDepartment of Biotechnology, University of Rijeka, Radmile Matejčić 2, Rijeka, Croatia.
Marina MarcelićDepartment of Physiology and Immunology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20, 51000, Rijeka, Croatia.
Kristina GrabušićDepartment of Biotechnology, University of Rijeka, Radmile Matejčić 2, Rijeka, Croatia.
University of Rijeka · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglia are resident brain macrophages with key roles in development and brain homeostasis. Cytomegalovirus (CMV) readily infects microglia cells, even as a possible primary target of infection in development. Effects of CMV infection on a cellular level in microglia are still unclear; therefore, the aim of this research was to assess the immunometabolic changes of BV-2 microglia cells following the murine cytomegalovirus (MCMV) infection. In light of that aim, we established an in vitro model of ramified BV-2 microglia (BV-2

Indexed as

AnimalsArginaseCell LineCulture Media, Serum-FreeEmbryo, MammalianFibroblastsGene Expression RegulationHerpesviridae InfectionsHost-Pathogen InteractionsHypoxia-Inducible Factor 1, alpha SubunitLectins, C-TypeMannose-Binding LectinsMannose ReceptorMiceMice, Inbred BALB CMicrogliaArg1 protein, mouseArginaseCulture Media, Serum-FreeHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitLectins, C-TypeMannose-Binding LectinsMannose ReceptorNitric Oxide Synthase Type IINos2 protein, mouseReceptors, Cell SurfaceBV-2 cellsMicrogliaMurine cytomegalovirus

Identifiers

PMID31025265
OpenAlexW2940506810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.