Evidence map›Paper›PMID 31025250›Full record

ArticleIn vitro cellular & developmental biology. Animal2019

Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells.

Zhihong Liao, Zhenkai Dai, Chenyu Cai, Xinheng Zhang, Aijun Li, Huanmin Zhang, Yiming Yan, Wencheng Lin, Yu Wu, Hongxin Li and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  3. Article
  4. Article
  5. Article
  6. Article
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  8. The interplay of autophagy and non-apoptotic cell death pathways.International review of cell and molecular biology · 2020
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Zhihong LiaoCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Zhenkai DaiCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Chenyu CaiCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Xinheng ZhangCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Aijun LiCollege of science and engineering, Jinan University, Guangzhou, 510632, People's Republic of China.
Huanmin ZhangAgriculture Research Service, Avian Disease and Oncology Laboratory, USDA, East Lansing, MI, 48823, USA.
Yiming YanCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Wencheng LinCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Yu WuCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Hongxin LiCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Haiyun LiCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China.
Qingmei XieCollege of Animal Science, South China Agricultural University and Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, 510642, People's Republic of China. qmx@scau.edu.cn.
Key Laboratory of Guangdong Province · CNSouth China Agricultural University · CNJinan University · CNMichigan Department of Agriculture and Rural Development · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atg5, as a switch of cell autophagy and apoptosis, plays an important regulatory role in the occurrence and development of autophagy. Atg5 has been reported to involve the autophagy process but little in the apoptotic process. Here, we constructed an Atg5

Indexed as

AnimalsApoptosisAutophagyAutophagy-Related Protein 5Cell LineCell ProliferationChickensGene Knockout TechniquesHumansMicrotubule-Associated ProteinsAutophagy-Related Protein 5Microtubule-Associated ProteinsApoptosisAtg5AutophagyCRISPR/CAS9DF-1 cells

Identifiers

PMID31025250
OpenAlexW2941605753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.