ReviewCurrent gastroenterology reports2019
Controversies in the Management of Functional Constipation in Children.
Review in Current gastroenterology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- The relationship between functional constipation and overweight/obesity in children: a systematic review and meta-analysis.Pediatric research · 2023Pooled it
- Comparison of Ziziphus jujube Mill. Syrup versus polyethylene glycol in children with functional constipation: a randomized clinical trial.Scientific reports · 2025Trial
- The use of two Comfort Young Child Formulas in the dietary management of toddlers with functional constipation: a randomized controlled trial.BMC pediatrics · 2022Trial
- Efficacy of Electro-acupuncture in Treatment of Functional Constipation: A Randomized Controlled Trial.Current medical science · 2020Trial
- Transition from pediatric to adult healthcare for patients with chronic functional constipation: a scoping review and provider insight.Pediatric surgery international · 2026Article
- Sensation of Incomplete Evacuation in Patients With Fecal Incontinence: A Cross-Sectional Study of a Tertiary Referral Cohort.Neurogastroenterology and motility · 2026Article
- Therapeutic efficacy of Jichuan decoction in slow-transit constipation: focus on gut microbiota modulation.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- Development and validation of a risk prediction model for functional constipation in school-aged children.BMC pediatrics · 2026Article
- Cluster analysis of research hotspots and trends in probiotics for constipation: A comprehensive bibliometric analysis (1977-2024).Medicine · 2026Article
- Microbiota-A Rescuing Modulator in Children Struggling with Functional Constipation.Microorganisms · 2025Review
- Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra-performance liquid chromatography.Animal models and experimental medicine · 2025Article
- Tethered cord syndrome (TCS) and constipation in children: a multifaceted approach (literature review).Annals of medicine and surgery (2012) · 2025Review
- Olive Oil Solution of Volatile Oil fromDrug design, development and therapy · 2025Article
- Prospective association between food protein-induced allergic proctocolitis in infancy and constipation after age 3.Journal of pediatric gastroenterology and nutrition · 2025Article
- Review
- Influence of the examination position and distension medium on the rectal sensory test in patients with functional constipation.BMC gastroenterology · 2024Article
- Article
- The oral cavity and intestinal microbiome in children with functional constipation.Scientific reports · 2024Article
- Safety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms.Paediatric drugs · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewFunctional constipation (FC) in children is a common health problem with reported worldwide prevalence rates up to 32.2%. The majority of children with constipation respond to oral laxative treatment. After 5 years of intensive treatment, however, approximately 50% of children remain symptomatic. To discuss the evidence for new treatments in these children, including pre- and probiotics, pelvic physiotherapy, prucalopride, sacral nerve stimulation, and surgery, and to highlight the controversies surrounding them. RECENT
findingsPre- and probiotics and prucalopride are not effective in the treatment of childhood constipation. Pelvic physiotherapy and sacral nerve stimulation are promising treatment options but larger trials are needed. Surgery for pediatric constipation is the treatment of last resort. Large, well-designed placebo-controlled trials with proper outcome measures, as suggested by the Rome foundation pediatric subcommittee on clinical trials, are necessary to provide more insight regarding the efficacy of new treatments in childhood constipation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.