Evidence map›Paper›PMID 31024882›Full record

ReviewFrontiers in chemistry2019

Gold Nanoparticles for Photothermal Cancer Therapy.

Jeremy B Vines, Jee-Hyun Yoon, Na-Eun Ryu, Dong-Jin Lim, Hansoo Park

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 305 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
305citing papers in PubMed, 3 pooled it
31.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

305 citing papers in PubMed, 3 syntheses or guidelines pooled it, 867 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Golden era of radiosensitizers.Frontiers in veterinary science · 2024
    Pooled it
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  19. Vaccine Adjuvants and Delivery Systems: A Comprehensive Review.International journal of molecular sciences · 2026
    Review
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245 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jeremy B VinesCasinbio USA, Birmingham, AL, United States.
Jee-Hyun YoonDepartment of Herbology, College of Korean Medicine, Woosuk University Jeonju, South Korea.
Na-Eun RyuSchool of Integrative Engineering, Chung-Ang University Seoul, South Korea.
Dong-Jin LimOtolaryngology Head and Neck Surgery, University of Alabama at Birmingham Birmingham, AL, United States.
Hansoo ParkSchool of Integrative Engineering, Chung-Ang University Seoul, South Korea.
Chung-Ang University · KRUniversity of Alabama at Birmingham · USWoosuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold is a multifunctional material that has been utilized in medicinal applications for centuries because it has been recognized for its bacteriostatic, anticorrosive, and antioxidative properties. Modern medicine makes routine, conventional use of gold and has even developed more advanced applications by taking advantage of its ability to be manufactured at the nanoscale and functionalized because of the presence of thiol and amine groups, allowing for the conjugation of various functional groups such as targeted antibodies or drug products. It has been shown that colloidal gold exhibits localized plasmon surface resonance (LPSR), meaning that gold nanoparticles can absorb light at specific wavelengths, resulting in photoacoustic and photothermal properties, making them potentially useful for hyperthermic cancer treatments and medical imaging applications. Modifying gold nanoparticle shape and size can change their LPSR photochemical activities, thereby also altering their photothermal and photoacoustic properties, allowing for the utilization of different wavelengths of light, such as light in the near-infrared spectrum. By manufacturing gold in a nanoscale format, it is possible to passively distribute the material through the body, where it can localize in tumors (which are characterized by leaky blood vessels) and be safely excreted through the urinary system. In this paper, we give a quick review of the structure, applications, recent advancements, and potential future directions for the utilization of gold nanoparticles in cancer therapeutics.

Indexed as

cancer therapeuticsgoldhyperthermiananoparticlesphoto-active property

Identifiers

PMID31024882
PMCPMC6460051
OpenAlexW2934897782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.