ArticleFrontiers in pediatrics2019
Zinner Syndrome in Pediatric Age: Issues in the Diagnosis and Treatment of a Rare Malformation Complex.
Article in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 36 citations in OpenAlex.
- Zinner syndrome: Late-Diagnosis in a 55-year-old male and favorable outcome after surgical excision - A case report and review of the literature.Urology case reports · 2026Article
- Posterior bladder-associated pelvic cystic lesion with histologic features consistent with mesenteric cyst in an infant with a functionally solitary kidney: a diagnostic uncertainty case report.Frontiers in pediatrics · 2026Article
- Diagnosis of Zinner syndrome: A case of rare occurrence.Radiology case reports · 2025Article
- Zinner syndrome, a rare congenital urogenital tract malformation: the first reported case in Indonesia.Fukushima journal of medical science · 2025Article
- Zinner's syndrome in two young middle-aged men: a case report and review of the literature.BMC urology · 2025Review
- Zinner Syndrome: Case report of atypical symptoms and literature.Urology case reports · 2025Article
- Zinner syndrome unveiled: Ectopic ureter and seminal vesicle cyst leading to urinary dysfunction: A case report.Radiology case reports · 2025Article
- A rare Zinner syndrome combined with testicular cancer: a case report.Frontiers in oncology · 2025Article
- A rare variant of zinner syndrome with ejaculatory duct cyst: case report and challenges in diagnosis and management.BMC urology · 2024Article
- Zinner syndrome with contralateral hydronephrosis: A rare congenital condition.Urology case reports · 2024Article
- Zinner syndrome in pediatric patients: rare disease leading to challenging management.Frontiers in pediatrics · 2024Article
- Successful treatment of ejaculation pain with silodosin in patient with Zinner syndrome: a case report.Translational andrology and urology · 2023Article
- Challenging clinical presentation of Zinner syndrome.Radiology case reports · 2023Article
- Zinner syndrome: a rare diagnosis in infancy.BMJ case reports · 2022Article
- Zinner syndrome - case report.Medicine and pharmacy reports · 2021Article
- Zinner Syndrome with Papillary Neoplasm: A Rare Case Report.Journal of Indian Association of Pediatric SurgeonsArticle
- Successful Laparoscopic Management of Zinner Syndrome in a Pediatric Patient.Journal of Indian Association of Pediatric SurgeonsArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinner syndrome (ZS) is the association of congenital seminal vesicle cysts and ipsilateral upper urinary tract anomalies, such as multicystic displastic kidney (MCDK). This condition is rare in pediatric age and both diagnosis and treatment are challenging. The aim of this study was to analyze the issues in diagnosis, management, and treatment of ZS in pediatric age. The medical records of two patients with ZS were examined. Furthermore, a review of the literature on this topic in pediatric age was performed. In our experience the diagnosis of ZS was incidentally achieved in the first months of life, as a consequence of studies performed for a prenatal diagnosis of MCDK. The first patient presented unspecific and transient symptoms, the second infant was completely asymptomatic. They were conservatively treated, with a long-term follow-up planned at least until adolescence. Fifty cases of ZS in pediatric age have been reported in the literature up to now. Only 12/50 were diagnosed in the first year of life. The diagnosis was demanding, as the clinical presentation was unspecific and the results at imaging studies needed a differential diagnosis with other retrovesical masses. More than 80% of these cases were asymptomatic at long-term follow-up. Therefore, a conservative management of ZS has been accepted for asymptomatic or poorly symptomatic patients, with occasional, transient, and unspecific symptoms, such as urinary tract infections or orchyepididimytis. As the surgical management is challenging, it is proposed only in those symptomatic patients. In conclusion, ZS is rare in pediatric age. However, it should be considered in the differential diagnosis of cystic masses within the pelvis in males with ipsilateral renal anomalies. A conservative treatment with a long-term follow-up is a safe option in the management of asymptomatic or poorly symptomatic patients, thus reserving the surgical approach only in those cases with symptoms.
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