ArticleInternational journal of ophthalmology2019
Abnormalities of interhemispheric functional connectivity in individuals with acute eye pain: a resting-state fMRI study.
Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Alterations of interhemispheric functional connectivity in patients with hypertensive retinopathy using voxel-mirrored homotopic connectivity: a resting state fMRI study.International journal of ophthalmology · 2025Article
- Voxel-Mirrored Homotopic Connectivity Is Altered in Meibomian Gland Dysfunction Patients That Are Morbidly Obese.Brain sciences · 2022Article
- Abnormal interhemispheric functional connectivity in patients with primary dysmenorrhea: a resting-state functional MRI study.Quantitative imaging in medicine and surgery · 2022Article
- Machine learning analysis reveals abnormal functional network hubs in the primary angle-closure glaucoma patients.Frontiers in human neuroscience · 2022Article
- Aberrant interhemispheric functional reciprocities of the default mode network and motor network in subcortical ischemic stroke patients with motor impairment: A longitudinal study.Frontiers in neurology · 2022Article
- Alternations of interhemispheric functional connectivity in children with strabismus and amblyopia: a resting-state fMRI study.Scientific reports · 2021Article
- Regional brain changes in patients with diabetic optic neuropathy: a resting-state functional magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2021Article
- Interhemispheric Functional Connectivity Alterations in Diabetic Optic Neuropathy: A Resting-State Functional Magnetic Resonance Imaging Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Resting-State Functional MRI Study Demonstrates That the Density of Functional Connectivity Density Mapping Changes in Patients with Acute Eye Pain.Journal of pain research · 2020Article
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study the changes of the resting state functional connectivity (rsFC) between acute eye pain (EP) subjects and healthy controls (HCs) in the two hemispheres by using voxel-mirrored homotopic connectivity (VMHC) method.
methodsTotally 20 patients with EP and 20 HCs were enrolled, sex, age, and education were matched, and all subjects were examined by functional magnetic resonance imaging (fMRI) scans at resting-state. The changes of rsFC between the hemispheres were evaluated by the VMHC method according to Gaussian random field (GRF) theory. In order to identify the VMHC, as biomarkers for distinguishing EP and from HC, the receiver operating characteristic curves (ROC) had been analyzed. The relationships were evaluated with Pearson correlation analysis between the mean VMHC signal values and clinical features in these patients.
resultsBy comparing with health subjects, the significant decreased VMHC values was observed in lingual/calcarine (Brodmann area, BA 30), precentral/postcentral gyrus (PreCG/PosCG; BA 4) and medial frontal gyrus (MFG; BA 8) (false discovery rate corrected <0.01) in the acute EP individuals. The accuracy of area under curve was excellent indicated by the ROC curve analysis of each brain regions.
conclusionOur study demonstrates preliminary evidence of disrupted interhemispheric rsFC in acute EP in sensorimotor and limbic system and somatosensory cortex, which might give some useful information for understanding the neurological mechanisms in acute EP individuals.
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